Epidemic models with differential susceptibility and stagedprogression and their dynamics

We formulate and study epidemic models with differential susceptibilities andstaged-progressions, based on systems of ordinary differential equations, fordisease transmission where the susceptibility of susceptible individuals varyand the infective individuals progress the disease gradually through...

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Bibliographic Details
Main Authors: James M. Hyman, Jia Li
Format: Article
Language:English
Published: AIMS Press 2009-02-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2009.6.321
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Summary:We formulate and study epidemic models with differential susceptibilities andstaged-progressions, based on systems of ordinary differential equations, fordisease transmission where the susceptibility of susceptible individuals varyand the infective individuals progress the disease gradually through stageswith different infectiousness in each stage. We consider the contact rates tobe proportional to the total population or constant such that the infectionrates have a bilinear or standard form, respectively. We derive explicitformulas for the reproductive number $R_0$, and show that the infection-freeequilibrium is globally asymptotically stable if $R_01$.
ISSN:1551-0018