Insulin Therapy: “When Saviour Turns Hostile”

Insulin is the cornerstone of type 1 diabetes mellitus (T1DM) treatment. Insulin allergy in patients with T1DM on insulin is an uncommon problem that might manifest itself as immediate or delayed symptoms after injections. We present 2 cases: the first is a 17-year-old girl who was diagnosed with T1...

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Bibliographic Details
Main Authors: Dhanya Soodhana Mohan, Vani Hebbal Nagarajappa, Santhosh Olety Sathyanarayana, Sahana M. Srinivas, Raghupathy Palany
Format: Article
Language:English
Published: Knowledge E 2022-03-01
Series:Dubai Diabetes and Endocrinology Journal
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Online Access:https://www.karger.com/Article/FullText/522562
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Summary:Insulin is the cornerstone of type 1 diabetes mellitus (T1DM) treatment. Insulin allergy in patients with T1DM on insulin is an uncommon problem that might manifest itself as immediate or delayed symptoms after injections. We present 2 cases: the first is a 17-year-old girl who was diagnosed with T1DM at the age of 14 and has had several skin lesions at injection sites over the past 2 months that have not responded to antibiotics. The second case involves a 4-year-old boy who was diagnosed with T1DM at the age of 15 months and had non-tender, erythematous, and indurated lesions. Insulin hypersensitivity was detected in both cases, thus newer analogues were administered instead of regular and isophane insulin, and the lesions dramatically reduced.
ISSN:2673-1797
2673-1738