Hemolytic uremic syndrome outbreak in Turkey in 2011
The aim of this retrospective multicenter study was to define the epidemiological and clinical features and prognostic factors of the first diarrhea-related hemolytic uremic syndrome (D+HUS) outbreak in Turkey in 2011. All pediatric nephrology centers in Turkey were asked about D+HUS patients...
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| Format: | Article |
| Language: | English |
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Hacettepe University Institute of Child Health
2013-06-01
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| Series: | The Turkish Journal of Pediatrics |
| Online Access: | https://turkjpediatr.org/article/view/1494 |
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| author | Zelal Ekinci Ozan Özkaya Nida Dinçel Nurver Akıncı Kaan Gülleroğlu Ali Delibaş İpek Akil Yılmaz Tabel Faruk Öktem Emel Işıyel Hasan Dursun Kenan Bek Ismail Dursun Zübeyde Gündüz Sare Gülfem Akyüz Nur Canpolat Harika Alpay Cengiz Candan Oğuz Söylemezoğlu |
| author_facet | Zelal Ekinci Ozan Özkaya Nida Dinçel Nurver Akıncı Kaan Gülleroğlu Ali Delibaş İpek Akil Yılmaz Tabel Faruk Öktem Emel Işıyel Hasan Dursun Kenan Bek Ismail Dursun Zübeyde Gündüz Sare Gülfem Akyüz Nur Canpolat Harika Alpay Cengiz Candan Oğuz Söylemezoğlu |
| author_sort | Zelal Ekinci |
| collection | DOAJ |
| description |
The aim of this retrospective multicenter study was to define the epidemiological and clinical features and prognostic factors of the first diarrhea-related hemolytic uremic syndrome (D+HUS) outbreak in Turkey in 2011. All pediatric nephrology centers in Turkey were asked about D+HUS patients via e-mail. Seventy D+HUS patients (median age: 5.7 years) participated. The seasonal peak was around the 7th, 8th and 9th months with 44 cases, centered in the east Marmara region. No causative agent could be identified. The rate of neurological complications and mortality was 21.4% and 4.2%, respectively. Eculizumab was used in four cases. Two of them had severe neurological complications despite plasma exchange. Elevated polymorphonuclear leukocyte count during hospital admission was the predictor of both severe disease and poor outcome. Duration of prodrome was the predictor of poor outcome (p |
| format | Article |
| id | doaj-art-4af4b2c324a44f49b75c41f88fcec6ee |
| institution | DOAJ |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2013-06-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-4af4b2c324a44f49b75c41f88fcec6ee2025-08-20T03:01:15ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212013-06-01553Hemolytic uremic syndrome outbreak in Turkey in 2011Zelal Ekinci0Ozan ÖzkayaNida DinçelNurver AkıncıKaan GülleroğluAli Delibaşİpek AkilYılmaz TabelFaruk ÖktemEmel IşıyelHasan DursunKenan BekIsmail DursunZübeyde GündüzSare Gülfem AkyüzNur CanpolatHarika AlpayCengiz CandanOğuz SöylemezoğluDivision of Pediatric Nephrology, Department of Pediatrics, 1Kocaeli University Faculty of Medicine, Kocaeli, Turkey. zekinci@outlook.com. The aim of this retrospective multicenter study was to define the epidemiological and clinical features and prognostic factors of the first diarrhea-related hemolytic uremic syndrome (D+HUS) outbreak in Turkey in 2011. All pediatric nephrology centers in Turkey were asked about D+HUS patients via e-mail. Seventy D+HUS patients (median age: 5.7 years) participated. The seasonal peak was around the 7th, 8th and 9th months with 44 cases, centered in the east Marmara region. No causative agent could be identified. The rate of neurological complications and mortality was 21.4% and 4.2%, respectively. Eculizumab was used in four cases. Two of them had severe neurological complications despite plasma exchange. Elevated polymorphonuclear leukocyte count during hospital admission was the predictor of both severe disease and poor outcome. Duration of prodrome was the predictor of poor outcome (phttps://turkjpediatr.org/article/view/1494 |
| spellingShingle | Zelal Ekinci Ozan Özkaya Nida Dinçel Nurver Akıncı Kaan Gülleroğlu Ali Delibaş İpek Akil Yılmaz Tabel Faruk Öktem Emel Işıyel Hasan Dursun Kenan Bek Ismail Dursun Zübeyde Gündüz Sare Gülfem Akyüz Nur Canpolat Harika Alpay Cengiz Candan Oğuz Söylemezoğlu Hemolytic uremic syndrome outbreak in Turkey in 2011 The Turkish Journal of Pediatrics |
| title | Hemolytic uremic syndrome outbreak in Turkey in 2011 |
| title_full | Hemolytic uremic syndrome outbreak in Turkey in 2011 |
| title_fullStr | Hemolytic uremic syndrome outbreak in Turkey in 2011 |
| title_full_unstemmed | Hemolytic uremic syndrome outbreak in Turkey in 2011 |
| title_short | Hemolytic uremic syndrome outbreak in Turkey in 2011 |
| title_sort | hemolytic uremic syndrome outbreak in turkey in 2011 |
| url | https://turkjpediatr.org/article/view/1494 |
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