Moderating effects of resilience and depression on social support and life satisfaction in patients with IBD: a cross-sectional study

Abstract Inflammatory bowel disease (IBD) significantly impaired patients’ quality of life and might have affected their life satisfaction. Based on the psychosocial stress model and the conservation of resources theory, this study aimed to investigate the level of life satisfaction among patients w...

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Main Authors: Jia-Mei Shen, Yan Zhang, Ying Xie, Hui-Lin Ye, Jian-Rong Zhou, Shi-Qi Xie
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-06221-4
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author Jia-Mei Shen
Yan Zhang
Ying Xie
Hui-Lin Ye
Jian-Rong Zhou
Shi-Qi Xie
author_facet Jia-Mei Shen
Yan Zhang
Ying Xie
Hui-Lin Ye
Jian-Rong Zhou
Shi-Qi Xie
author_sort Jia-Mei Shen
collection DOAJ
description Abstract Inflammatory bowel disease (IBD) significantly impaired patients’ quality of life and might have affected their life satisfaction. Based on the psychosocial stress model and the conservation of resources theory, this study aimed to investigate the level of life satisfaction among patients with IBD and explored the relationships among social support, resilience, and life satisfaction in these patients. A sample of 153 IBD patients completed questionnaires assessing social support (SSRS), resilience (RS-IBD), depression (PHQ-9), and life satisfaction (SWLS). Correlation and mediation analyses were conducted using SPSS PROCESS macro. Results revealed that 73.9% of patients reported life satisfaction (SWLS ≥ 21). Significant correlations emerged between life satisfaction and social support (r = 0.537, p < 0.01), resilience (r = 0.522, p < 0.01), and depression (r = − 0.325, p < 0.01). Mediation analysis indicated that resilience partially mediated the effect of social support on life satisfaction (β = 0.101, 95% CI: 0.025–0.177), accounting for 27.67% of the total effect. Social support was associated with life satisfaction (64.38% of total effect), while resilience and depression jointly mediated 8.77% of the effect. Comprehensive intervention programs focusing on enhancing social support, improving resilience, and alleviating depression are crucial for boosting IBD patients’ life satisfaction.
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spelling doaj-art-4af4280e51a54ea3962c6e22c544e52d2025-08-20T03:37:27ZengNature PortfolioScientific Reports2045-23222025-07-0115111010.1038/s41598-025-06221-4Moderating effects of resilience and depression on social support and life satisfaction in patients with IBD: a cross-sectional studyJia-Mei Shen0Yan Zhang1Ying Xie2Hui-Lin Ye3Jian-Rong Zhou4Shi-Qi Xie5Department of Nursing, The First Affiliated Hospital of Chongqing Medical UniversityDepartment of Nursing, The First Affiliated Hospital of Chongqing Medical UniversityDepartment of Nursing, The First Affiliated Hospital of Chongqing Medical UniversityDepartment of Nursing, The First Affiliated Hospital of Chongqing Medical UniversityShool of Nursing, Chongqing Medical UniversityShool of Nursing, Chongqing Medical UniversityAbstract Inflammatory bowel disease (IBD) significantly impaired patients’ quality of life and might have affected their life satisfaction. Based on the psychosocial stress model and the conservation of resources theory, this study aimed to investigate the level of life satisfaction among patients with IBD and explored the relationships among social support, resilience, and life satisfaction in these patients. A sample of 153 IBD patients completed questionnaires assessing social support (SSRS), resilience (RS-IBD), depression (PHQ-9), and life satisfaction (SWLS). Correlation and mediation analyses were conducted using SPSS PROCESS macro. Results revealed that 73.9% of patients reported life satisfaction (SWLS ≥ 21). Significant correlations emerged between life satisfaction and social support (r = 0.537, p < 0.01), resilience (r = 0.522, p < 0.01), and depression (r = − 0.325, p < 0.01). Mediation analysis indicated that resilience partially mediated the effect of social support on life satisfaction (β = 0.101, 95% CI: 0.025–0.177), accounting for 27.67% of the total effect. Social support was associated with life satisfaction (64.38% of total effect), while resilience and depression jointly mediated 8.77% of the effect. Comprehensive intervention programs focusing on enhancing social support, improving resilience, and alleviating depression are crucial for boosting IBD patients’ life satisfaction.https://doi.org/10.1038/s41598-025-06221-4Inflammatory bowel diseaseResilienceSocial supportDepressionLife satisfaction
spellingShingle Jia-Mei Shen
Yan Zhang
Ying Xie
Hui-Lin Ye
Jian-Rong Zhou
Shi-Qi Xie
Moderating effects of resilience and depression on social support and life satisfaction in patients with IBD: a cross-sectional study
Scientific Reports
Inflammatory bowel disease
Resilience
Social support
Depression
Life satisfaction
title Moderating effects of resilience and depression on social support and life satisfaction in patients with IBD: a cross-sectional study
title_full Moderating effects of resilience and depression on social support and life satisfaction in patients with IBD: a cross-sectional study
title_fullStr Moderating effects of resilience and depression on social support and life satisfaction in patients with IBD: a cross-sectional study
title_full_unstemmed Moderating effects of resilience and depression on social support and life satisfaction in patients with IBD: a cross-sectional study
title_short Moderating effects of resilience and depression on social support and life satisfaction in patients with IBD: a cross-sectional study
title_sort moderating effects of resilience and depression on social support and life satisfaction in patients with ibd a cross sectional study
topic Inflammatory bowel disease
Resilience
Social support
Depression
Life satisfaction
url https://doi.org/10.1038/s41598-025-06221-4
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