Sveir epidemiological model with varying infectivity and distributed delays

In this paper, based on an SEIR epidemiologicalmodel with distributed delays to account for varying infectivity, weintroduce a vaccination compartment, leading to an SVEIR model. Byemploying direct Lyapunov method and LaSalle's invariance principle,we construct appropriate functionals that inte...

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Main Authors: Jinliang Wang, Gang Huang, Yasuhiro Takeuchi, Shengqiang Liu
Format: Article
Language:English
Published: AIMS Press 2011-05-01
Series:Mathematical Biosciences and Engineering
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Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2011.8.875
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author Jinliang Wang
Gang Huang
Yasuhiro Takeuchi
Shengqiang Liu
author_facet Jinliang Wang
Gang Huang
Yasuhiro Takeuchi
Shengqiang Liu
author_sort Jinliang Wang
collection DOAJ
description In this paper, based on an SEIR epidemiologicalmodel with distributed delays to account for varying infectivity, weintroduce a vaccination compartment, leading to an SVEIR model. Byemploying direct Lyapunov method and LaSalle's invariance principle,we construct appropriate functionals that integrate over past statesto establish global asymptotic stability conditions, which arecompletely determined by the basic reproduction number$\mathcal{R}_0^V$. More precisely, it is shown that, if$\mathcal{R}_0^V\leq 1$, then the disease free equilibrium isglobally asymptotically stable; if $\mathcal{R}_0^V> 1$, then there exists a unique endemic equilibrium which isglobally asymptotically stable. Mathematicalresults suggest that vaccination is helpful for disease control bydecreasing the basic reproduction number. However, there is anecessary condition for successful elimination of disease. If thetime for the vaccinees to obtain immunity or the possibility forthem to be infected before acquiring immunity can be neglected, thiscondition would be satisfied and the disease can always be eradicatedby some suitable vaccination strategies. This may lead toover-evaluating the effect of vaccination.
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institution Kabale University
issn 1551-0018
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publishDate 2011-05-01
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spelling doaj-art-4aef6fa7c80c4b59ac331ff3fd3c3d9c2025-01-24T02:02:00ZengAIMS PressMathematical Biosciences and Engineering1551-00182011-05-018387588810.3934/mbe.2011.8.875Sveir epidemiological model with varying infectivity and distributed delaysJinliang Wang0Gang Huang1Yasuhiro Takeuchi2Shengqiang Liu3Department of Mathematics, Harbin Institute of Technology, Harbin 150001Department of Mathematics, Harbin Institute of Technology, Harbin 150001Department of Mathematics, Harbin Institute of Technology, Harbin 150001Department of Mathematics, Harbin Institute of Technology, Harbin 150001In this paper, based on an SEIR epidemiologicalmodel with distributed delays to account for varying infectivity, weintroduce a vaccination compartment, leading to an SVEIR model. Byemploying direct Lyapunov method and LaSalle's invariance principle,we construct appropriate functionals that integrate over past statesto establish global asymptotic stability conditions, which arecompletely determined by the basic reproduction number$\mathcal{R}_0^V$. More precisely, it is shown that, if$\mathcal{R}_0^V\leq 1$, then the disease free equilibrium isglobally asymptotically stable; if $\mathcal{R}_0^V> 1$, then there exists a unique endemic equilibrium which isglobally asymptotically stable. Mathematicalresults suggest that vaccination is helpful for disease control bydecreasing the basic reproduction number. However, there is anecessary condition for successful elimination of disease. If thetime for the vaccinees to obtain immunity or the possibility forthem to be infected before acquiring immunity can be neglected, thiscondition would be satisfied and the disease can always be eradicatedby some suitable vaccination strategies. This may lead toover-evaluating the effect of vaccination.https://www.aimspress.com/article/doi/10.3934/mbe.2011.8.875global stability.vaccination strategydistributed delaysvaryinginfectivityepidemic model
spellingShingle Jinliang Wang
Gang Huang
Yasuhiro Takeuchi
Shengqiang Liu
Sveir epidemiological model with varying infectivity and distributed delays
Mathematical Biosciences and Engineering
global stability.
vaccination strategy
distributed delays
varyinginfectivity
epidemic model
title Sveir epidemiological model with varying infectivity and distributed delays
title_full Sveir epidemiological model with varying infectivity and distributed delays
title_fullStr Sveir epidemiological model with varying infectivity and distributed delays
title_full_unstemmed Sveir epidemiological model with varying infectivity and distributed delays
title_short Sveir epidemiological model with varying infectivity and distributed delays
title_sort sveir epidemiological model with varying infectivity and distributed delays
topic global stability.
vaccination strategy
distributed delays
varyinginfectivity
epidemic model
url https://www.aimspress.com/article/doi/10.3934/mbe.2011.8.875
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AT ganghuang sveirepidemiologicalmodelwithvaryinginfectivityanddistributeddelays
AT yasuhirotakeuchi sveirepidemiologicalmodelwithvaryinginfectivityanddistributeddelays
AT shengqiangliu sveirepidemiologicalmodelwithvaryinginfectivityanddistributeddelays