Blood Culture-Negative but Clinically Diagnosed Infective Endocarditis Complicated by Intracranial Mycotic Aneurysm, Brain Abscess, and Posterior Tibial Artery Pseudoaneurysm
Blood culture-negative endocarditis is often severe and difficult to diagnose. It is necessary to emphasize the importance for the early diagnosis and accurate treatment of blood culture-negative endocarditis. Here, we described the relevant clinical information of a blood culture-negative but clini...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
|
| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2018/1236502 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832549301537996800 |
|---|---|
| author | Chao Jiang Haibin Lu Yaoqiang Guo Li Zhu Tianqi Luo Wendy Ziai Jian Wang |
| author_facet | Chao Jiang Haibin Lu Yaoqiang Guo Li Zhu Tianqi Luo Wendy Ziai Jian Wang |
| author_sort | Chao Jiang |
| collection | DOAJ |
| description | Blood culture-negative endocarditis is often severe and difficult to diagnose. It is necessary to emphasize the importance for the early diagnosis and accurate treatment of blood culture-negative endocarditis. Here, we described the relevant clinical information of a blood culture-negative but clinically diagnosed infective endocarditis complicated by intracranial mycotic aneurysm, brain abscess, and posterior tibial artery pseudoaneurysm. This patient was a 65-year-old man with a 9-month history of intermittent fever and died in the end for the progressive neurological deterioration. Although the blood culture is negative, this patient was clinically diagnosed as infective endocarditis according to Duke criteria. This patient course was complicated not only by cerebral embolism, intracranial mycotic aneurysm, and brain abscess but also by posterior tibial artery aneurysm of the lower extremity. The clinical findings of this patient suggest that the confirmatory microbiology is essential for the treatment of blood culture-negative infective endocarditis. Clinicians should be aware of the detriment of blood culture-negative infective endocarditis for its multiple complications may occur in one patient. The delayed etiological diagnosis and insufficient treatment may aggregate the clinical outcome of blood culture-negative infective endocarditis. |
| format | Article |
| id | doaj-art-4aee48e7d69641caa81b5706d50f34ff |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-4aee48e7d69641caa81b5706d50f34ff2025-02-03T06:11:32ZengWileyCase Reports in Neurological Medicine2090-66682090-66762018-01-01201810.1155/2018/12365021236502Blood Culture-Negative but Clinically Diagnosed Infective Endocarditis Complicated by Intracranial Mycotic Aneurysm, Brain Abscess, and Posterior Tibial Artery PseudoaneurysmChao Jiang0Haibin Lu1Yaoqiang Guo2Li Zhu3Tianqi Luo4Wendy Ziai5Jian Wang6Department of Neurology, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, ChinaDepartment of Neurology, Henan Provincial Chest Hospital, Zhengzhou 450000, ChinaDepartment of Neurology, Henan Provincial Chest Hospital, Zhengzhou 450000, ChinaDepartment of Neurology, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, ChinaDepartment of Anesthesiology/Critical Care Medicine, Johns Hopkins University, School of Medicine, Baltimore, MD, USADepartment of Anesthesiology/Critical Care Medicine, Johns Hopkins University, School of Medicine, Baltimore, MD, USADepartment of Anesthesiology/Critical Care Medicine, Johns Hopkins University, School of Medicine, Baltimore, MD, USABlood culture-negative endocarditis is often severe and difficult to diagnose. It is necessary to emphasize the importance for the early diagnosis and accurate treatment of blood culture-negative endocarditis. Here, we described the relevant clinical information of a blood culture-negative but clinically diagnosed infective endocarditis complicated by intracranial mycotic aneurysm, brain abscess, and posterior tibial artery pseudoaneurysm. This patient was a 65-year-old man with a 9-month history of intermittent fever and died in the end for the progressive neurological deterioration. Although the blood culture is negative, this patient was clinically diagnosed as infective endocarditis according to Duke criteria. This patient course was complicated not only by cerebral embolism, intracranial mycotic aneurysm, and brain abscess but also by posterior tibial artery aneurysm of the lower extremity. The clinical findings of this patient suggest that the confirmatory microbiology is essential for the treatment of blood culture-negative infective endocarditis. Clinicians should be aware of the detriment of blood culture-negative infective endocarditis for its multiple complications may occur in one patient. The delayed etiological diagnosis and insufficient treatment may aggregate the clinical outcome of blood culture-negative infective endocarditis.http://dx.doi.org/10.1155/2018/1236502 |
| spellingShingle | Chao Jiang Haibin Lu Yaoqiang Guo Li Zhu Tianqi Luo Wendy Ziai Jian Wang Blood Culture-Negative but Clinically Diagnosed Infective Endocarditis Complicated by Intracranial Mycotic Aneurysm, Brain Abscess, and Posterior Tibial Artery Pseudoaneurysm Case Reports in Neurological Medicine |
| title | Blood Culture-Negative but Clinically Diagnosed Infective Endocarditis Complicated by Intracranial Mycotic Aneurysm, Brain Abscess, and Posterior Tibial Artery Pseudoaneurysm |
| title_full | Blood Culture-Negative but Clinically Diagnosed Infective Endocarditis Complicated by Intracranial Mycotic Aneurysm, Brain Abscess, and Posterior Tibial Artery Pseudoaneurysm |
| title_fullStr | Blood Culture-Negative but Clinically Diagnosed Infective Endocarditis Complicated by Intracranial Mycotic Aneurysm, Brain Abscess, and Posterior Tibial Artery Pseudoaneurysm |
| title_full_unstemmed | Blood Culture-Negative but Clinically Diagnosed Infective Endocarditis Complicated by Intracranial Mycotic Aneurysm, Brain Abscess, and Posterior Tibial Artery Pseudoaneurysm |
| title_short | Blood Culture-Negative but Clinically Diagnosed Infective Endocarditis Complicated by Intracranial Mycotic Aneurysm, Brain Abscess, and Posterior Tibial Artery Pseudoaneurysm |
| title_sort | blood culture negative but clinically diagnosed infective endocarditis complicated by intracranial mycotic aneurysm brain abscess and posterior tibial artery pseudoaneurysm |
| url | http://dx.doi.org/10.1155/2018/1236502 |
| work_keys_str_mv | AT chaojiang bloodculturenegativebutclinicallydiagnosedinfectiveendocarditiscomplicatedbyintracranialmycoticaneurysmbrainabscessandposteriortibialarterypseudoaneurysm AT haibinlu bloodculturenegativebutclinicallydiagnosedinfectiveendocarditiscomplicatedbyintracranialmycoticaneurysmbrainabscessandposteriortibialarterypseudoaneurysm AT yaoqiangguo bloodculturenegativebutclinicallydiagnosedinfectiveendocarditiscomplicatedbyintracranialmycoticaneurysmbrainabscessandposteriortibialarterypseudoaneurysm AT lizhu bloodculturenegativebutclinicallydiagnosedinfectiveendocarditiscomplicatedbyintracranialmycoticaneurysmbrainabscessandposteriortibialarterypseudoaneurysm AT tianqiluo bloodculturenegativebutclinicallydiagnosedinfectiveendocarditiscomplicatedbyintracranialmycoticaneurysmbrainabscessandposteriortibialarterypseudoaneurysm AT wendyziai bloodculturenegativebutclinicallydiagnosedinfectiveendocarditiscomplicatedbyintracranialmycoticaneurysmbrainabscessandposteriortibialarterypseudoaneurysm AT jianwang bloodculturenegativebutclinicallydiagnosedinfectiveendocarditiscomplicatedbyintracranialmycoticaneurysmbrainabscessandposteriortibialarterypseudoaneurysm |