Extensive Growth of an Anaplastic Meningioma

We present the case of a 30-year-old male patient with an almost complete destruction of the calvarial bone through an anaplastic meningioma diagnosed in line with dizziness. Neuroimaging revealed an extensive growing, contrast enhancing lesion expanding at the supra- and infratentorial convexity, i...

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Main Authors: Hajrullah Ahmeti, Homajoun Maslehaty, Athanasios K. Petridis, Alexandros Doukas, Mehran Mahvash, Harald Barth, H. M. Mehdorn
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2013/527184
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author Hajrullah Ahmeti
Homajoun Maslehaty
Athanasios K. Petridis
Alexandros Doukas
Mehran Mahvash
Harald Barth
H. M. Mehdorn
author_facet Hajrullah Ahmeti
Homajoun Maslehaty
Athanasios K. Petridis
Alexandros Doukas
Mehran Mahvash
Harald Barth
H. M. Mehdorn
author_sort Hajrullah Ahmeti
collection DOAJ
description We present the case of a 30-year-old male patient with an almost complete destruction of the calvarial bone through an anaplastic meningioma diagnosed in line with dizziness. Neuroimaging revealed an extensive growing, contrast enhancing lesion expanding at the supra- and infratentorial convexity, infiltrating and destroying large parts of the skull, and infiltrating the skin. Due to progressive ataxia and dysarthria with proven tumor growth in the posterior fossa in the continuing course, parts of the tumor were resected. A surgical procedure with the aim of complete tumor resection in a curative manner was not possible. Six months after the first operation, due to a new tumor progression, most extensive tumor resection was performed. Due to the aggressive and destructive growth with a high rate of recurrence and tendency of metastases, anaplastic meningiomas can be termed as malignant tumors. The extrinsic growth masks the tumor until they reach a size, which makes these tumors almost unresectable. In the best case scenarios, the five-year survival is about 50%. With the presented case, we would like to show the aggressive behavior of anaplastic meningiomas in a very illustrative way. Chemotherapy, radiotherapy, and surgery reach their limits in this tumor entity.
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spelling doaj-art-4aebb9d9cb77474aa055fc4ab19b632c2025-02-03T05:59:16ZengWileyCase Reports in Neurological Medicine2090-66682090-66762013-01-01201310.1155/2013/527184527184Extensive Growth of an Anaplastic MeningiomaHajrullah Ahmeti0Homajoun Maslehaty1Athanasios K. Petridis2Alexandros Doukas3Mehran Mahvash4Harald Barth5H. M. Mehdorn6Department of Neurosurgery, University Hospitals Schleswig-Holstein, Campus Kiel, Arnold-Heller Street 3, 24105 Kiel, GermanyDepartment of Neurosurgery, University Hospitals Schleswig-Holstein, Campus Kiel, Arnold-Heller Street 3, 24105 Kiel, GermanyDepartment of Neurosurgery, University Hospitals Schleswig-Holstein, Campus Kiel, Arnold-Heller Street 3, 24105 Kiel, GermanyDepartment of Neurosurgery, University Hospitals Schleswig-Holstein, Campus Kiel, Arnold-Heller Street 3, 24105 Kiel, GermanyDepartment of Neurosurgery, University Hospitals Schleswig-Holstein, Campus Kiel, Arnold-Heller Street 3, 24105 Kiel, GermanyDepartment of Neurosurgery, University Hospitals Schleswig-Holstein, Campus Kiel, Arnold-Heller Street 3, 24105 Kiel, GermanyDepartment of Neurosurgery, University Hospitals Schleswig-Holstein, Campus Kiel, Arnold-Heller Street 3, 24105 Kiel, GermanyWe present the case of a 30-year-old male patient with an almost complete destruction of the calvarial bone through an anaplastic meningioma diagnosed in line with dizziness. Neuroimaging revealed an extensive growing, contrast enhancing lesion expanding at the supra- and infratentorial convexity, infiltrating and destroying large parts of the skull, and infiltrating the skin. Due to progressive ataxia and dysarthria with proven tumor growth in the posterior fossa in the continuing course, parts of the tumor were resected. A surgical procedure with the aim of complete tumor resection in a curative manner was not possible. Six months after the first operation, due to a new tumor progression, most extensive tumor resection was performed. Due to the aggressive and destructive growth with a high rate of recurrence and tendency of metastases, anaplastic meningiomas can be termed as malignant tumors. The extrinsic growth masks the tumor until they reach a size, which makes these tumors almost unresectable. In the best case scenarios, the five-year survival is about 50%. With the presented case, we would like to show the aggressive behavior of anaplastic meningiomas in a very illustrative way. Chemotherapy, radiotherapy, and surgery reach their limits in this tumor entity.http://dx.doi.org/10.1155/2013/527184
spellingShingle Hajrullah Ahmeti
Homajoun Maslehaty
Athanasios K. Petridis
Alexandros Doukas
Mehran Mahvash
Harald Barth
H. M. Mehdorn
Extensive Growth of an Anaplastic Meningioma
Case Reports in Neurological Medicine
title Extensive Growth of an Anaplastic Meningioma
title_full Extensive Growth of an Anaplastic Meningioma
title_fullStr Extensive Growth of an Anaplastic Meningioma
title_full_unstemmed Extensive Growth of an Anaplastic Meningioma
title_short Extensive Growth of an Anaplastic Meningioma
title_sort extensive growth of an anaplastic meningioma
url http://dx.doi.org/10.1155/2013/527184
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