Hybrid Technique of Lamellar Keratoplasty (DMEK-S)

Purpose: To evaluate the outcomes of the hybrid technique of posterior lamellar keratoplasty (DMEK-S). Materials and Methods: 71 eyes of 55 patients enrolled in a single-center study underwent posterior lamellar keratoplasty with a hybrid lamella DMEK-S implanted using a solution implantation techni...

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Main Authors: Pavel Studeny, Deli Sivekova, Katerina Liehneova, Magdalena Vokrojova, Pavel Kuchynka
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2013/254383
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author Pavel Studeny
Deli Sivekova
Katerina Liehneova
Magdalena Vokrojova
Pavel Kuchynka
author_facet Pavel Studeny
Deli Sivekova
Katerina Liehneova
Magdalena Vokrojova
Pavel Kuchynka
author_sort Pavel Studeny
collection DOAJ
description Purpose: To evaluate the outcomes of the hybrid technique of posterior lamellar keratoplasty (DMEK-S). Materials and Methods: 71 eyes of 55 patients enrolled in a single-center study underwent posterior lamellar keratoplasty with a hybrid lamella DMEK-S implanted using a solution implantation technique, owing to endothelial dysfunction. The outcome measures studied were visual acuity and endothelial cell density. Results: The rate of endothelial cell loss caused by surgery was 43.8%. During followups, we observed the stabilization of postoperative findings, or at minimum a very low rate of corneal endothelial cell loss. The UCDVA and BCDVA dramatically improved postoperatively. The rebubbling rate in our group of patients was 61.9%. We replaced the lamella due to its failure or malfunction in 17 patients (23.9%). Conclusion: In summary, DMEK-S combines the advantages of DSEK/DSAEK and DMEK. The central zone of bare Descemet’s membrane and endothelium allows for very good visual outcomes, and the peripheral rim allows for better manipulation of the lamella during implantation. It is an effective method of treating the endothelial dysfunction of various etiologies, but the high complication rate needs to be addressed before widespread implementation of the technique in the future.
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institution Kabale University
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publishDate 2013-01-01
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series Journal of Ophthalmology
spelling doaj-art-4ad5e9a1e9e74225be39f5381e2daaaf2025-02-03T05:58:28ZengWileyJournal of Ophthalmology2090-004X2090-00582013-01-01201310.1155/2013/254383254383Hybrid Technique of Lamellar Keratoplasty (DMEK-S)Pavel Studeny0Deli Sivekova1Katerina Liehneova2Magdalena Vokrojova3Pavel Kuchynka4Ophthalmology Department, Medical Faculty of Charles University and Teaching Hospital Kralovske Vinohrady, Srobarova 50, Prague 100 34, Czech RepublicOphthalmology Department, Medical Faculty of Charles University and Teaching Hospital Kralovske Vinohrady, Srobarova 50, Prague 100 34, Czech RepublicOphthalmology Department, Medical Faculty of Charles University and Teaching Hospital Kralovske Vinohrady, Srobarova 50, Prague 100 34, Czech RepublicOphthalmology Department, Medical Faculty of Charles University and Teaching Hospital Kralovske Vinohrady, Srobarova 50, Prague 100 34, Czech RepublicOphthalmology Department, Medical Faculty of Charles University and Teaching Hospital Kralovske Vinohrady, Srobarova 50, Prague 100 34, Czech RepublicPurpose: To evaluate the outcomes of the hybrid technique of posterior lamellar keratoplasty (DMEK-S). Materials and Methods: 71 eyes of 55 patients enrolled in a single-center study underwent posterior lamellar keratoplasty with a hybrid lamella DMEK-S implanted using a solution implantation technique, owing to endothelial dysfunction. The outcome measures studied were visual acuity and endothelial cell density. Results: The rate of endothelial cell loss caused by surgery was 43.8%. During followups, we observed the stabilization of postoperative findings, or at minimum a very low rate of corneal endothelial cell loss. The UCDVA and BCDVA dramatically improved postoperatively. The rebubbling rate in our group of patients was 61.9%. We replaced the lamella due to its failure or malfunction in 17 patients (23.9%). Conclusion: In summary, DMEK-S combines the advantages of DSEK/DSAEK and DMEK. The central zone of bare Descemet’s membrane and endothelium allows for very good visual outcomes, and the peripheral rim allows for better manipulation of the lamella during implantation. It is an effective method of treating the endothelial dysfunction of various etiologies, but the high complication rate needs to be addressed before widespread implementation of the technique in the future.http://dx.doi.org/10.1155/2013/254383
spellingShingle Pavel Studeny
Deli Sivekova
Katerina Liehneova
Magdalena Vokrojova
Pavel Kuchynka
Hybrid Technique of Lamellar Keratoplasty (DMEK-S)
Journal of Ophthalmology
title Hybrid Technique of Lamellar Keratoplasty (DMEK-S)
title_full Hybrid Technique of Lamellar Keratoplasty (DMEK-S)
title_fullStr Hybrid Technique of Lamellar Keratoplasty (DMEK-S)
title_full_unstemmed Hybrid Technique of Lamellar Keratoplasty (DMEK-S)
title_short Hybrid Technique of Lamellar Keratoplasty (DMEK-S)
title_sort hybrid technique of lamellar keratoplasty dmek s
url http://dx.doi.org/10.1155/2013/254383
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AT magdalenavokrojova hybridtechniqueoflamellarkeratoplastydmeks
AT pavelkuchynka hybridtechniqueoflamellarkeratoplastydmeks