Hybrid Technique of Lamellar Keratoplasty (DMEK-S)
Purpose: To evaluate the outcomes of the hybrid technique of posterior lamellar keratoplasty (DMEK-S). Materials and Methods: 71 eyes of 55 patients enrolled in a single-center study underwent posterior lamellar keratoplasty with a hybrid lamella DMEK-S implanted using a solution implantation techni...
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Format: | Article |
Language: | English |
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Wiley
2013-01-01
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Series: | Journal of Ophthalmology |
Online Access: | http://dx.doi.org/10.1155/2013/254383 |
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author | Pavel Studeny Deli Sivekova Katerina Liehneova Magdalena Vokrojova Pavel Kuchynka |
author_facet | Pavel Studeny Deli Sivekova Katerina Liehneova Magdalena Vokrojova Pavel Kuchynka |
author_sort | Pavel Studeny |
collection | DOAJ |
description | Purpose: To evaluate the outcomes of the hybrid technique of posterior lamellar keratoplasty (DMEK-S). Materials and Methods: 71 eyes of 55 patients enrolled in a single-center study underwent posterior lamellar keratoplasty with a hybrid lamella DMEK-S implanted using a solution implantation technique, owing to endothelial dysfunction. The outcome measures studied were visual acuity and endothelial cell density. Results: The rate of endothelial cell loss caused by surgery was 43.8%. During followups, we observed the stabilization of postoperative findings, or at minimum a very low rate of corneal endothelial cell loss. The UCDVA and BCDVA dramatically improved postoperatively. The rebubbling rate in our group of patients was 61.9%. We replaced the lamella due to its failure or malfunction in 17 patients (23.9%). Conclusion: In summary, DMEK-S combines the advantages of DSEK/DSAEK and DMEK. The central zone of bare Descemet’s membrane and endothelium allows for very good visual outcomes, and the peripheral rim allows for better manipulation of the lamella during implantation. It is an effective method of treating the endothelial dysfunction of various etiologies, but the high complication rate needs to be addressed before widespread implementation of the technique in the future. |
format | Article |
id | doaj-art-4ad5e9a1e9e74225be39f5381e2daaaf |
institution | Kabale University |
issn | 2090-004X 2090-0058 |
language | English |
publishDate | 2013-01-01 |
publisher | Wiley |
record_format | Article |
series | Journal of Ophthalmology |
spelling | doaj-art-4ad5e9a1e9e74225be39f5381e2daaaf2025-02-03T05:58:28ZengWileyJournal of Ophthalmology2090-004X2090-00582013-01-01201310.1155/2013/254383254383Hybrid Technique of Lamellar Keratoplasty (DMEK-S)Pavel Studeny0Deli Sivekova1Katerina Liehneova2Magdalena Vokrojova3Pavel Kuchynka4Ophthalmology Department, Medical Faculty of Charles University and Teaching Hospital Kralovske Vinohrady, Srobarova 50, Prague 100 34, Czech RepublicOphthalmology Department, Medical Faculty of Charles University and Teaching Hospital Kralovske Vinohrady, Srobarova 50, Prague 100 34, Czech RepublicOphthalmology Department, Medical Faculty of Charles University and Teaching Hospital Kralovske Vinohrady, Srobarova 50, Prague 100 34, Czech RepublicOphthalmology Department, Medical Faculty of Charles University and Teaching Hospital Kralovske Vinohrady, Srobarova 50, Prague 100 34, Czech RepublicOphthalmology Department, Medical Faculty of Charles University and Teaching Hospital Kralovske Vinohrady, Srobarova 50, Prague 100 34, Czech RepublicPurpose: To evaluate the outcomes of the hybrid technique of posterior lamellar keratoplasty (DMEK-S). Materials and Methods: 71 eyes of 55 patients enrolled in a single-center study underwent posterior lamellar keratoplasty with a hybrid lamella DMEK-S implanted using a solution implantation technique, owing to endothelial dysfunction. The outcome measures studied were visual acuity and endothelial cell density. Results: The rate of endothelial cell loss caused by surgery was 43.8%. During followups, we observed the stabilization of postoperative findings, or at minimum a very low rate of corneal endothelial cell loss. The UCDVA and BCDVA dramatically improved postoperatively. The rebubbling rate in our group of patients was 61.9%. We replaced the lamella due to its failure or malfunction in 17 patients (23.9%). Conclusion: In summary, DMEK-S combines the advantages of DSEK/DSAEK and DMEK. The central zone of bare Descemet’s membrane and endothelium allows for very good visual outcomes, and the peripheral rim allows for better manipulation of the lamella during implantation. It is an effective method of treating the endothelial dysfunction of various etiologies, but the high complication rate needs to be addressed before widespread implementation of the technique in the future.http://dx.doi.org/10.1155/2013/254383 |
spellingShingle | Pavel Studeny Deli Sivekova Katerina Liehneova Magdalena Vokrojova Pavel Kuchynka Hybrid Technique of Lamellar Keratoplasty (DMEK-S) Journal of Ophthalmology |
title | Hybrid Technique of Lamellar Keratoplasty (DMEK-S) |
title_full | Hybrid Technique of Lamellar Keratoplasty (DMEK-S) |
title_fullStr | Hybrid Technique of Lamellar Keratoplasty (DMEK-S) |
title_full_unstemmed | Hybrid Technique of Lamellar Keratoplasty (DMEK-S) |
title_short | Hybrid Technique of Lamellar Keratoplasty (DMEK-S) |
title_sort | hybrid technique of lamellar keratoplasty dmek s |
url | http://dx.doi.org/10.1155/2013/254383 |
work_keys_str_mv | AT pavelstudeny hybridtechniqueoflamellarkeratoplastydmeks AT delisivekova hybridtechniqueoflamellarkeratoplastydmeks AT katerinaliehneova hybridtechniqueoflamellarkeratoplastydmeks AT magdalenavokrojova hybridtechniqueoflamellarkeratoplastydmeks AT pavelkuchynka hybridtechniqueoflamellarkeratoplastydmeks |