Integrins and Their Extracellular Matrix Ligands in Lymphangiogenesis and Lymph Node Metastasis
In the 1970s, the late Judah Folkman postulated that tumors grow proportionately to their blood supply and that tumor angiogenesis removed this limitation promoting growth and metastasis. Work over the past 40 years, varying from molecular examination to clinical trials, verified this hypothesis and...
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Main Authors: | Jie Chen, J. Steven Alexander, A. Wayne Orr |
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Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
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Series: | International Journal of Cell Biology |
Online Access: | http://dx.doi.org/10.1155/2012/853703 |
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