Unilateral Optic Neuritis: A Rare Complication after Measles-Mumps-Rubella Vaccination in a 30-Year-Old Woman

Purpose. To report a case of unilateral optic neuritis following Measles-Mumps-Rubella (MMR) vaccination. Methods. A 30-year-old female developed unilateral optic neuritis five days after a Measles-Mumps-Rubella (MMR) booster vaccination. The patient displayed unilateral involvement, with severe vis...

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Main Authors: Chiara De Giacinto, Elvira Guaglione, Pia E. Leon, Rossella D’Aloisio, Odilla Vattovani, Giuseppe Ravalico, Daniele Tognetto
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2016/8740264
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author Chiara De Giacinto
Elvira Guaglione
Pia E. Leon
Rossella D’Aloisio
Odilla Vattovani
Giuseppe Ravalico
Daniele Tognetto
author_facet Chiara De Giacinto
Elvira Guaglione
Pia E. Leon
Rossella D’Aloisio
Odilla Vattovani
Giuseppe Ravalico
Daniele Tognetto
author_sort Chiara De Giacinto
collection DOAJ
description Purpose. To report a case of unilateral optic neuritis following Measles-Mumps-Rubella (MMR) vaccination. Methods. A 30-year-old female developed unilateral optic neuritis five days after a Measles-Mumps-Rubella (MMR) booster vaccination. The patient displayed unilateral involvement, with severe visual loss. However, visual acuity improved significantly after four days of intravenous steroid therapy with 500 mg/day of methylprednisolone. Conclusions. Optic neuritis is one of the rare complications associated with the mumps, measles, and rubella vaccine. It may be a toxic reaction to the nonviral component of the vaccine, but the exact etiology is unknown. Postvaccination neuritis is generally bilateral and usually affects children. In adults, unilateral optic neuritis is usually correlated with multiple sclerosis (MS).
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institution Kabale University
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series Case Reports in Ophthalmological Medicine
spelling doaj-art-4abaec78aca64de995c4e44e6aef86ba2025-02-03T07:23:51ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302016-01-01201610.1155/2016/87402648740264Unilateral Optic Neuritis: A Rare Complication after Measles-Mumps-Rubella Vaccination in a 30-Year-Old WomanChiara De Giacinto0Elvira Guaglione1Pia E. Leon2Rossella D’Aloisio3Odilla Vattovani4Giuseppe Ravalico5Daniele Tognetto6University Eye Clinic of Trieste, Ospedale Maggiore, Piazza dell’Ospitale 1, 34125 Trieste, ItalyUniversity Eye Clinic of Trieste, Ospedale Maggiore, Piazza dell’Ospitale 1, 34125 Trieste, ItalyUniversity Eye Clinic of Trieste, Ospedale Maggiore, Piazza dell’Ospitale 1, 34125 Trieste, ItalyUniversity Eye Clinic of Trieste, Ospedale Maggiore, Piazza dell’Ospitale 1, 34125 Trieste, ItalyUniversity Eye Clinic of Trieste, Ospedale Maggiore, Piazza dell’Ospitale 1, 34125 Trieste, ItalyUniversity Eye Clinic of Trieste, Ospedale Maggiore, Piazza dell’Ospitale 1, 34125 Trieste, ItalyUniversity Eye Clinic of Trieste, Ospedale Maggiore, Piazza dell’Ospitale 1, 34125 Trieste, ItalyPurpose. To report a case of unilateral optic neuritis following Measles-Mumps-Rubella (MMR) vaccination. Methods. A 30-year-old female developed unilateral optic neuritis five days after a Measles-Mumps-Rubella (MMR) booster vaccination. The patient displayed unilateral involvement, with severe visual loss. However, visual acuity improved significantly after four days of intravenous steroid therapy with 500 mg/day of methylprednisolone. Conclusions. Optic neuritis is one of the rare complications associated with the mumps, measles, and rubella vaccine. It may be a toxic reaction to the nonviral component of the vaccine, but the exact etiology is unknown. Postvaccination neuritis is generally bilateral and usually affects children. In adults, unilateral optic neuritis is usually correlated with multiple sclerosis (MS).http://dx.doi.org/10.1155/2016/8740264
spellingShingle Chiara De Giacinto
Elvira Guaglione
Pia E. Leon
Rossella D’Aloisio
Odilla Vattovani
Giuseppe Ravalico
Daniele Tognetto
Unilateral Optic Neuritis: A Rare Complication after Measles-Mumps-Rubella Vaccination in a 30-Year-Old Woman
Case Reports in Ophthalmological Medicine
title Unilateral Optic Neuritis: A Rare Complication after Measles-Mumps-Rubella Vaccination in a 30-Year-Old Woman
title_full Unilateral Optic Neuritis: A Rare Complication after Measles-Mumps-Rubella Vaccination in a 30-Year-Old Woman
title_fullStr Unilateral Optic Neuritis: A Rare Complication after Measles-Mumps-Rubella Vaccination in a 30-Year-Old Woman
title_full_unstemmed Unilateral Optic Neuritis: A Rare Complication after Measles-Mumps-Rubella Vaccination in a 30-Year-Old Woman
title_short Unilateral Optic Neuritis: A Rare Complication after Measles-Mumps-Rubella Vaccination in a 30-Year-Old Woman
title_sort unilateral optic neuritis a rare complication after measles mumps rubella vaccination in a 30 year old woman
url http://dx.doi.org/10.1155/2016/8740264
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