CXCL7 enhances RANKL-induced osteoclastogenesis via the activation of ERK/NFATc1 signaling pathway in inflammatory arthritis
Abstract Background Rheumatoid arthritis (RA) with anti-citrullinated protein/peptide antibodies (ACPA + RA) demonstrates more significant radiographic damage compared to ACPA-negative RA (ACPA- RA). Chemokine-activated signaling pathways contribute to the regulation of the bone formation and resorp...
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| Main Authors: | Xinyu Wang, Lin Sun, Zhuo An, Changhong Li, Jinxia Zhao |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-02-01
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| Series: | Arthritis Research & Therapy |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13075-025-03502-1 |
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