Identification of EPHB4 as a potential causal gene and therapeutic target for endometriosis using Mendelian randomization

Identification of EPHB4 as a potential causal gene and therapeutic target for endometriosis using Mendelian randomization

Abstract Objectives Endometriosis is a common condition among women, characterized by chronic pain and infertility, presenting significant challenges for clinicians. This study aims to identify potential druggable targets to offer new therapeutic approaches. Method We utilized the summary-data-based...

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Bibliographic Details
Main Authors: Shaohua Ling, Delong Xie, Lifang Huang, Siqi Huang, Chun Tian, Liying Huang, Rong Chen, Li Qin, Xiao Qin
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Hereditas
Subjects:
Endometriosis
Mendelian randomization
Druggable genome
EPHB4
Colocalization analysis
Online Access:https://doi.org/10.1186/s41065-025-00457-w
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