Polycythaemia Secondary to Hormone Replacement Therapy with Tibolone

We present the case report of a patient with severe polycythaemia associated with tibolone. In our 65-year-old postmenopausal patient who initially presented with haemoglobin 203 g/L [115–160] and haematocrit 0.63 [0.32–0.47], the cessation of tibolone, a synthetic hormone replacement therapy, led t...

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Main Authors: Laura Staples, Tamara Milder, Philip Young-Ill Choi
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2017/3476349
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author Laura Staples
Tamara Milder
Philip Young-Ill Choi
author_facet Laura Staples
Tamara Milder
Philip Young-Ill Choi
author_sort Laura Staples
collection DOAJ
description We present the case report of a patient with severe polycythaemia associated with tibolone. In our 65-year-old postmenopausal patient who initially presented with haemoglobin 203 g/L [115–160] and haematocrit 0.63 [0.32–0.47], the cessation of tibolone, a synthetic hormone replacement therapy, led to a dramatic and sustained resolution of this patient’s polycythaemia to normal haematological values. Tibolone possesses oestrogenic, androgenic, and progestogenic properties. Tibolone therapy may be an infrequently recognized contributor towards polycythaemia in postmenopausal patients presenting to haematology clinics.
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institution Kabale University
issn 2090-6560
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series Case Reports in Hematology
spelling doaj-art-4a406bf699c64e978afe124ea1f8e0772025-02-03T00:59:45ZengWileyCase Reports in Hematology2090-65602090-65792017-01-01201710.1155/2017/34763493476349Polycythaemia Secondary to Hormone Replacement Therapy with TiboloneLaura Staples0Tamara Milder1Philip Young-Ill Choi2Haematology Department, The Canberra Hospital, Canberra, ACT, AustraliaEndocrinology Department, The Canberra Hospital, Canberra, ACT, AustraliaHaematology Department, The Canberra Hospital, Canberra, ACT, AustraliaWe present the case report of a patient with severe polycythaemia associated with tibolone. In our 65-year-old postmenopausal patient who initially presented with haemoglobin 203 g/L [115–160] and haematocrit 0.63 [0.32–0.47], the cessation of tibolone, a synthetic hormone replacement therapy, led to a dramatic and sustained resolution of this patient’s polycythaemia to normal haematological values. Tibolone possesses oestrogenic, androgenic, and progestogenic properties. Tibolone therapy may be an infrequently recognized contributor towards polycythaemia in postmenopausal patients presenting to haematology clinics.http://dx.doi.org/10.1155/2017/3476349
spellingShingle Laura Staples
Tamara Milder
Philip Young-Ill Choi
Polycythaemia Secondary to Hormone Replacement Therapy with Tibolone
Case Reports in Hematology
title Polycythaemia Secondary to Hormone Replacement Therapy with Tibolone
title_full Polycythaemia Secondary to Hormone Replacement Therapy with Tibolone
title_fullStr Polycythaemia Secondary to Hormone Replacement Therapy with Tibolone
title_full_unstemmed Polycythaemia Secondary to Hormone Replacement Therapy with Tibolone
title_short Polycythaemia Secondary to Hormone Replacement Therapy with Tibolone
title_sort polycythaemia secondary to hormone replacement therapy with tibolone
url http://dx.doi.org/10.1155/2017/3476349
work_keys_str_mv AT laurastaples polycythaemiasecondarytohormonereplacementtherapywithtibolone
AT tamaramilder polycythaemiasecondarytohormonereplacementtherapywithtibolone
AT philipyoungillchoi polycythaemiasecondarytohormonereplacementtherapywithtibolone