Spillable Semisolid Contents of Cystic Ameloblastoma Habour Tumour Cells
Background: Ameloblastoma is a cystic jaw tumor and often contains tumor fluid, blood clots, semisolid cheesy, or gelatinous materials. The histologic demonstrations of tumor invasion of the cystic contents by ameloblastoma cells have not been reported in African and western literature. The high rec...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-07-01
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| Series: | International Journal of Medicine and Health Development |
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| Online Access: | https://doi.org/10.4103/ijmh.ijmh_25_24 |
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| author | Mark C. Nwoga |
| author_facet | Mark C. Nwoga |
| author_sort | Mark C. Nwoga |
| collection | DOAJ |
| description | Background: Ameloblastoma is a cystic jaw tumor and often contains tumor fluid, blood clots, semisolid cheesy, or gelatinous materials. The histologic demonstrations of tumor invasion of the cystic contents by ameloblastoma cells have not been reported in African and western literature. The high recurrence rate of ameloblastoma has often been attributed to tumor spills during surgery. Objective: To assess for the presence of tumor cells in the semisolid contents of cystic ameloblastoma. Materials and Methods: This is a 10-year (August 2013 to July 2023) retrospective study of excisional specimens of ameloblastoma with cystic cavity contents of either blood clot, gelatinous, or cheesy materials at a tertiary health institution in Enugu, Nigeria. Results: Thirty-one resected specimens were documented with semisolid materials of blood clots, gelatinous, or cheesy materials. The male-to-female ratio, mean age, and mean duration were 1:1.7, 20.4 ± 6.6 years, and 42.0 ± 26.5 months, respectively. The specimens were all from the posterior mandible (100.0%), and 87.5% of the tumors were of the solid ameloblastoma type based on histologic study. Gelatinous material (50.0%) had the most frequent semisolid cystic content. Microscopic examination of the semisolid cavity contents demonstrated plexiform infiltrative tumors, islands, neoplastic cystic linings, stromal stellate cells, and inflammatory cells in 50% of the semisolid cystic content (blood clots, gelatinous, and cheesy materials). Conclusion: Ameloblastoma cells often invade semisolid cystic materials and could contribute to recurrences when spilled into tissues. |
| format | Article |
| id | doaj-art-4a395896729b4538974722a482f07f1b |
| institution | Kabale University |
| issn | 2635-3695 2667-2863 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Medicine and Health Development |
| spelling | doaj-art-4a395896729b4538974722a482f07f1b2025-01-25T10:09:59ZengWolters Kluwer Medknow PublicationsInternational Journal of Medicine and Health Development2635-36952667-28632024-07-0129324725110.4103/ijmh.ijmh_25_24Spillable Semisolid Contents of Cystic Ameloblastoma Habour Tumour CellsMark C. NwogaBackground: Ameloblastoma is a cystic jaw tumor and often contains tumor fluid, blood clots, semisolid cheesy, or gelatinous materials. The histologic demonstrations of tumor invasion of the cystic contents by ameloblastoma cells have not been reported in African and western literature. The high recurrence rate of ameloblastoma has often been attributed to tumor spills during surgery. Objective: To assess for the presence of tumor cells in the semisolid contents of cystic ameloblastoma. Materials and Methods: This is a 10-year (August 2013 to July 2023) retrospective study of excisional specimens of ameloblastoma with cystic cavity contents of either blood clot, gelatinous, or cheesy materials at a tertiary health institution in Enugu, Nigeria. Results: Thirty-one resected specimens were documented with semisolid materials of blood clots, gelatinous, or cheesy materials. The male-to-female ratio, mean age, and mean duration were 1:1.7, 20.4 ± 6.6 years, and 42.0 ± 26.5 months, respectively. The specimens were all from the posterior mandible (100.0%), and 87.5% of the tumors were of the solid ameloblastoma type based on histologic study. Gelatinous material (50.0%) had the most frequent semisolid cystic content. Microscopic examination of the semisolid cavity contents demonstrated plexiform infiltrative tumors, islands, neoplastic cystic linings, stromal stellate cells, and inflammatory cells in 50% of the semisolid cystic content (blood clots, gelatinous, and cheesy materials). Conclusion: Ameloblastoma cells often invade semisolid cystic materials and could contribute to recurrences when spilled into tissues.https://doi.org/10.4103/ijmh.ijmh_25_24ameloblastomablood clotcheesy materialgelatinous materialtumor spill |
| spellingShingle | Mark C. Nwoga Spillable Semisolid Contents of Cystic Ameloblastoma Habour Tumour Cells International Journal of Medicine and Health Development ameloblastoma blood clot cheesy material gelatinous material tumor spill |
| title | Spillable Semisolid Contents of Cystic Ameloblastoma Habour Tumour Cells |
| title_full | Spillable Semisolid Contents of Cystic Ameloblastoma Habour Tumour Cells |
| title_fullStr | Spillable Semisolid Contents of Cystic Ameloblastoma Habour Tumour Cells |
| title_full_unstemmed | Spillable Semisolid Contents of Cystic Ameloblastoma Habour Tumour Cells |
| title_short | Spillable Semisolid Contents of Cystic Ameloblastoma Habour Tumour Cells |
| title_sort | spillable semisolid contents of cystic ameloblastoma habour tumour cells |
| topic | ameloblastoma blood clot cheesy material gelatinous material tumor spill |
| url | https://doi.org/10.4103/ijmh.ijmh_25_24 |
| work_keys_str_mv | AT markcnwoga spillablesemisolidcontentsofcysticameloblastomahabourtumourcells |