Methyl-Arginine Profile of Brain from Aged PINK1-KO+A53T-SNCA Mice Suggests Altered Mitochondrial Biogenesis
Hereditary Parkinson’s disease can be triggered by an autosomal dominant overdose of alpha-Synuclein (SNCA) or the autosomal recessive deficiency of PINK1. We recently showed that the combination of PINK1-knockout with overexpression of A53T-SNCA in double mutant (DM) mice potentiates phenotypes and...
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Main Authors: | Georg Auburger, Suzana Gispert, Nadine Brehm |
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Format: | Article |
Language: | English |
Published: |
Wiley
2016-01-01
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Series: | Parkinson's Disease |
Online Access: | http://dx.doi.org/10.1155/2016/4686185 |
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