Surgical Resection Followed by Stereotactic Radiosurgery (S+SRS) Versus SRS Alone for Large Posterior Fossa Brain Metastases: A Comparative Analysis of Outcomes and Factors Guiding Treatment Modality Selection

Surgical Resection Followed by Stereotactic Radiosurgery (S+SRS) Versus SRS Alone for Large Posterior Fossa Brain Metastases: A Comparative Analysis of Outcomes and Factors Guiding Treatment Modality Selection

Background/Objectives: Around 20% of cancer patients will develop brain metastases (BrMs), with 15–25% occurring in the posterior fossa (PF). Although the effectiveness of systemic therapies is increasing, surgery followed by stereotactic radiosurgery (S+SRS) versus definitive SRS remains the mainst...

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Main Authors: Ruth Lau, Enrique Gutierrez-Valencia, Anna Santiago, Carolyn Lai, Danyal Baber Ahmed, Parnian Habibi, Normand Laperriere, Tatiana Conrad, Barbara-Ann Millar, Mark Bernstein, Paul Kongkham, Gelareh Zadeh, David Benjamin Shultz, Aristotelis Kalyvas
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Brain Sciences
Subjects:
brain metastases
posterior fossa
neurosurgery
stereotactic radiosurgery
Online Access:https://www.mdpi.com/2076-3425/14/11/1059
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