Elucidating the potential of EGFR mutated NSCLC and identifying its multitargeted inhibitors

Elucidating the potential of EGFR mutated NSCLC and identifying its multitargeted inhibitors

Abstract Lung cancer is the leading cause of cancer-related fatalities globally, accounting for the highest mortality rate among both men and women. Mutations in the epidermal growth factor receptor (EGFR) gene are frequently found in non-small cell lung cancer (NSCLC). Since curcumin and CB[2]UN su...

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Bibliographic Details
Main Authors: Anakha D. Rajeeve, Ramasamy Yamuna, P. K. Krishnan Namboori
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Lung cancer
EGFR
Cucurbituril
Dodecagonal strategy
Multitargeted inhibitors
Molecular dynamics simulation
Online Access:https://doi.org/10.1038/s41598-024-83868-5
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