Genetic variation reveals the therapeutic potential of BRSK2 in idiopathic pulmonary fibrosis

Genetic variation reveals the therapeutic potential of BRSK2 in idiopathic pulmonary fibrosis

Abstract Background Current research underscores the need to better understand the pathogenic mechanisms and treatment strategies for idiopathic pulmonary fibrosis (IPF). This study aimed to identify key targets involved in the progression of IPF. Methods We employed Mendelian randomization (MR) wit...

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Bibliographic Details
Main Authors: Zhe Chen, Mingyang Tang, Nan Wang, Jiangjiang Liu, Xiaoyan Tan, Haitao Ma, Jing Luo, Kai Xie
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Medicine
Subjects:
Causal pathways
Idiopathic pulmonary fibrosis
Therapeutic targets
BRSK2
Online Access:https://doi.org/10.1186/s12916-025-03848-y
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