Administration of Iodine-125 Seeds Promotes Apoptosis in Cholangiocarcinoma through the PI3K/Akt Pathway
Purpose. We aimed to examine the effects of 125I seeds on the gene expression of Bcl-2, Bax, and PI3K/Akt pathway components in cholangiocarcinoma cells. Methods. In vitro, human cholangiocarcinoma RBE cells were treated with 125I seeds (0.39 mCi or 0.85 mCi) for 72 h, 120 h, and 168 h. Cell prolife...
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Main Authors: | Junqing Lin, Leye Yan, Xiaolong Wang, Zhengzhong Wu, Kun Ke, Xin Lin, Ning Huang, Weizhu Yang |
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Format: | Article |
Language: | English |
Published: |
Wiley
2022-01-01
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Series: | Advances in Polymer Technology |
Online Access: | http://dx.doi.org/10.1155/2022/6934934 |
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