Expert consensus and recommendations on the live attenuated hepatitis A vaccine and immunization practices in India
While Hepatitis A Virus (HAV) vaccination in global immunization programs has shown a virtual elimination of the disease within few years of the vaccination program, changing epidemiological landscape in India underscores the need for evidence-based, updated guidance on immunization practices. In Ma...
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Taylor & Francis Group
2025-12-01
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| Series: | Human Vaccines & Immunotherapeutics |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/21645515.2024.2447643 |
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| author | Nitin Shah M.M.A. Faridi Sheila Bhave Apurba Ghosh S. Balasubramanian Vidya Arankalle Raju Shah Amar Jeet Chitkara Arun Wadhwa Jaydeep Chaudhry Ramesh Srinivasan M. Surendranath Amita Sapru Monjori Mitra |
| author_facet | Nitin Shah M.M.A. Faridi Sheila Bhave Apurba Ghosh S. Balasubramanian Vidya Arankalle Raju Shah Amar Jeet Chitkara Arun Wadhwa Jaydeep Chaudhry Ramesh Srinivasan M. Surendranath Amita Sapru Monjori Mitra |
| author_sort | Nitin Shah |
| collection | DOAJ |
| description | While Hepatitis A Virus (HAV) vaccination in global immunization programs has shown a virtual elimination of the disease within few years of the vaccination program, changing epidemiological landscape in India underscores the need for evidence-based, updated guidance on immunization practices. In May 2024, a panel of 15 distinguished opinion leaders and an organizing committee convened for an intensive, face-to-face advisory board meeting on high burden of HAV infection among adults, increased mortality rate in adolescents, symptomatic presentation in children, and evolving landscape globally and within India. Extensive comparable deliberations on long-term follow-up data from India and data from country of origin advocated immunogenicity, tolerability, and long-term protective effects of single-dose live attenuated HAV vaccine in children. Finally, a consensus was achieved on recognition of increased global attention toward HAV prevention through vaccination coverage. The need for a single dose of live attenuated HAV vaccine was an important outcome of this meeting. |
| format | Article |
| id | doaj-art-49d17eaccda54f6cb3d8a5fac5d97582 |
| institution | Kabale University |
| issn | 2164-5515 2164-554X |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj-art-49d17eaccda54f6cb3d8a5fac5d975822025-02-04T20:10:42ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2025-12-0121110.1080/21645515.2024.2447643Expert consensus and recommendations on the live attenuated hepatitis A vaccine and immunization practices in IndiaNitin Shah0M.M.A. Faridi1Sheila Bhave2Apurba Ghosh3S. Balasubramanian4Vidya Arankalle5Raju Shah6Amar Jeet Chitkara7Arun Wadhwa8Jaydeep Chaudhry9Ramesh Srinivasan10M. Surendranath11Amita Sapru12Monjori Mitra13Department of Paediatrics, P. D. Hinduja Hospital & Medical Research Centre, Mumbai, IndiaDepartment of Paediatrics and Neonatology, Era’s Lucknow Medical College and Hospital, Lucknow, Uttar Pradesh, IndiaDepartment of Paediatrics, KEM Hospital Research Centre, Pune, IndiaDepartment of Paediatrics, Institute of Child Health, Kolkata, IndiaDepartment of Pediatrics, Kanchi Kamakoti CHILDS Trust Hospital, Chennai, IndiaDepartment of Communicable Diseases, Interactive Research School for Health Affairs (IRSHA), Bharati Vidyapeeth (Deemed to be University), Pune, IndiaDepartment of Pediatrics, Ankur Children Hospital, Ahmedabad, Gujarat, IndiaDepartment of Pediatrics, Max Super Specialty Hospital, Delhi, IndiaDepartment of Pediatrics, Dr. Wadhwa’s Clinic, New Delhi, IndiaDepartment of Paediatrics, Institute of Child Health, Kolkata, IndiaDepartment of Gastroenterology, Apollo Hospitals, Hyderabad, IndiaDepartment of Pediatrics, Vijay Marie Hospital, Hyderabad, IndiaDepartment of Paediatrics, KEM Hospital Research Centre, Pune, IndiaDepartment of Paediatrics, Institute of Child Health, Kolkata, IndiaWhile Hepatitis A Virus (HAV) vaccination in global immunization programs has shown a virtual elimination of the disease within few years of the vaccination program, changing epidemiological landscape in India underscores the need for evidence-based, updated guidance on immunization practices. In May 2024, a panel of 15 distinguished opinion leaders and an organizing committee convened for an intensive, face-to-face advisory board meeting on high burden of HAV infection among adults, increased mortality rate in adolescents, symptomatic presentation in children, and evolving landscape globally and within India. Extensive comparable deliberations on long-term follow-up data from India and data from country of origin advocated immunogenicity, tolerability, and long-term protective effects of single-dose live attenuated HAV vaccine in children. Finally, a consensus was achieved on recognition of increased global attention toward HAV prevention through vaccination coverage. The need for a single dose of live attenuated HAV vaccine was an important outcome of this meeting.https://www.tandfonline.com/doi/10.1080/21645515.2024.2447643Hepatitis Aimmunogenicitylive attenuated vaccinetolerabilitysafety |
| spellingShingle | Nitin Shah M.M.A. Faridi Sheila Bhave Apurba Ghosh S. Balasubramanian Vidya Arankalle Raju Shah Amar Jeet Chitkara Arun Wadhwa Jaydeep Chaudhry Ramesh Srinivasan M. Surendranath Amita Sapru Monjori Mitra Expert consensus and recommendations on the live attenuated hepatitis A vaccine and immunization practices in India Human Vaccines & Immunotherapeutics Hepatitis A immunogenicity live attenuated vaccine tolerability safety |
| title | Expert consensus and recommendations on the live attenuated hepatitis A vaccine and immunization practices in India |
| title_full | Expert consensus and recommendations on the live attenuated hepatitis A vaccine and immunization practices in India |
| title_fullStr | Expert consensus and recommendations on the live attenuated hepatitis A vaccine and immunization practices in India |
| title_full_unstemmed | Expert consensus and recommendations on the live attenuated hepatitis A vaccine and immunization practices in India |
| title_short | Expert consensus and recommendations on the live attenuated hepatitis A vaccine and immunization practices in India |
| title_sort | expert consensus and recommendations on the live attenuated hepatitis a vaccine and immunization practices in india |
| topic | Hepatitis A immunogenicity live attenuated vaccine tolerability safety |
| url | https://www.tandfonline.com/doi/10.1080/21645515.2024.2447643 |
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