Markers of Sleep-Disordered Breathing and Prediabetes in US Adults
Background. Prediabetes is a preclinical stage in the hyperglycemia continuum where subjects are at increased risk of developing diabetes. Several studies reported a positive association between markers of sleep-disordered breathing (SDB) and diabetes. However, few studies investigated the relations...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2012/902324 |
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| author | Omayma Alshaarawy Srinivas Teppala Anoop Shankar |
| author_facet | Omayma Alshaarawy Srinivas Teppala Anoop Shankar |
| author_sort | Omayma Alshaarawy |
| collection | DOAJ |
| description | Background. Prediabetes is a preclinical stage in the hyperglycemia continuum where subjects are at increased risk of developing diabetes. Several studies reported a positive association between markers of sleep-disordered breathing (SDB) and diabetes. However, few studies investigated the relationship between SDB markers and prediabetes. Methods. We examined 5,685 participants ≥20 years from the National Health and Nutrition Examination Survey (NHANES) 2005–2008. The exposure of interest was SDB markers including sleep duration, snoring, snorting, and daytime sleepiness. The outcome was prediabetes (n=2058), among subjects free of diabetes. Results. SDB markers were associated with prediabetes. Compared to those without any sleep disturbance, the multivariable odds ratio (OR) (95% confidence interval (CI)) of prediabetes among those with three or more SDB markers was 1.69 (1.28–2.22). In subgroup analyses, the association between SDB markers and prediabetes was stronger among women (OR (95% CI) = 2.09 (1.36–3.23) when compared to men (1.52 (1.00–2.35)) and was present among non-Hispanic whites (2.66 (1.92–3.69)) and Mexican Americans (1.99 (1.13–3.48)), but not among non-Hispanic blacks (1.10 (0.70–1.73)). Conclusion. SDB markers were associated with prediabetes. This association was stronger in women and was present mainly in non-Hispanic whites and Mexican Americans. |
| format | Article |
| id | doaj-art-49cfcfc47b7c409c9aaac19974cf60cd |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-49cfcfc47b7c409c9aaac19974cf60cd2025-02-03T00:59:45ZengWileyInternational Journal of Endocrinology1687-83371687-83452012-01-01201210.1155/2012/902324902324Markers of Sleep-Disordered Breathing and Prediabetes in US AdultsOmayma Alshaarawy0Srinivas Teppala1Anoop Shankar2Department of Community Medicine, West Virginia University School of Medicine, 1 Medical Center Drive, P.O. Box 9190, Morgantown, WV 26506, USADepartment of Community Medicine, West Virginia University School of Medicine, 1 Medical Center Drive, P.O. Box 9190, Morgantown, WV 26506, USADepartment of Community Medicine, West Virginia University School of Medicine, 1 Medical Center Drive, P.O. Box 9190, Morgantown, WV 26506, USABackground. Prediabetes is a preclinical stage in the hyperglycemia continuum where subjects are at increased risk of developing diabetes. Several studies reported a positive association between markers of sleep-disordered breathing (SDB) and diabetes. However, few studies investigated the relationship between SDB markers and prediabetes. Methods. We examined 5,685 participants ≥20 years from the National Health and Nutrition Examination Survey (NHANES) 2005–2008. The exposure of interest was SDB markers including sleep duration, snoring, snorting, and daytime sleepiness. The outcome was prediabetes (n=2058), among subjects free of diabetes. Results. SDB markers were associated with prediabetes. Compared to those without any sleep disturbance, the multivariable odds ratio (OR) (95% confidence interval (CI)) of prediabetes among those with three or more SDB markers was 1.69 (1.28–2.22). In subgroup analyses, the association between SDB markers and prediabetes was stronger among women (OR (95% CI) = 2.09 (1.36–3.23) when compared to men (1.52 (1.00–2.35)) and was present among non-Hispanic whites (2.66 (1.92–3.69)) and Mexican Americans (1.99 (1.13–3.48)), but not among non-Hispanic blacks (1.10 (0.70–1.73)). Conclusion. SDB markers were associated with prediabetes. This association was stronger in women and was present mainly in non-Hispanic whites and Mexican Americans.http://dx.doi.org/10.1155/2012/902324 |
| spellingShingle | Omayma Alshaarawy Srinivas Teppala Anoop Shankar Markers of Sleep-Disordered Breathing and Prediabetes in US Adults International Journal of Endocrinology |
| title | Markers of Sleep-Disordered Breathing and Prediabetes in US Adults |
| title_full | Markers of Sleep-Disordered Breathing and Prediabetes in US Adults |
| title_fullStr | Markers of Sleep-Disordered Breathing and Prediabetes in US Adults |
| title_full_unstemmed | Markers of Sleep-Disordered Breathing and Prediabetes in US Adults |
| title_short | Markers of Sleep-Disordered Breathing and Prediabetes in US Adults |
| title_sort | markers of sleep disordered breathing and prediabetes in us adults |
| url | http://dx.doi.org/10.1155/2012/902324 |
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