HIF-1α contributes to proliferation and invasiveness of neuroblastoma cells via SHH signaling.

HIF-1α contributes to proliferation and invasiveness of neuroblastoma cells via SHH signaling.

The aim of this study was to investigate the effects of hypoxia-inducible factor-1α (HIF-1α) on the proliferation, migration and invasion of neuroblastoma (NB) cells and the mechanisms involved. We here initially used the real-time polymerase chain reaction (real-time PCR), Western blotting and immu...

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Bibliographic Details
Main Authors: Sheng Chen, Min Zhang, Lili Xing, Yue Wang, Yongtao Xiao, Yeming Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0121115&type=printable
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