Genome-Wide Analysis of Wound-Induced Polypeptide Genes in <i>Glycine max</i> and Their Expression Dynamics During Cyst Nematode Infection

Plant small peptides are critical regulators of various biological processes, including development and stress responses. Polypeptides within the DUF3774 family, known as wound-induced polypeptides (WIPs), have been identified as key players in pattern-triggered immunity (PTI) and defense mechanisms...

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Bibliographic Details
Main Authors: Wenshu Kang, Zicheng Sun, Jiayao Xu, Nawei Qi, Piao Lei
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Agronomy
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Online Access:https://www.mdpi.com/2073-4395/15/4/957
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Summary:Plant small peptides are critical regulators of various biological processes, including development and stress responses. Polypeptides within the DUF3774 family, known as wound-induced polypeptides (WIPs), have been identified as key players in pattern-triggered immunity (PTI) and defense mechanisms in <i>Arabidopsis</i>. In this study, the genome-wide identification of WIP genes in <i>Glycine max</i> was performed, followed by gene structure correction and validation using second-generation and full-length RNA sequencing data. A total of 31 <i>GmWIP</i> genes were identified and validated, mapped to chromosomes Gm06, Gm12, Gm13, and Gm06_scaffold_301. Phylogenetic analysis grouped these genes into five distinct clusters, with tandem duplication emerging as the primary mechanism for their expansion in the soybean genome. qRT-PCR analysis revealed dynamic and significant changes in <i>GmWIP</i> expression during soybean cyst nematode (SCN) infection in a susceptible soybean cultivar. Remarkably, 90% of the <i>GmWIP</i> genes were downregulated at the early stage of SCN infection (1 dpi), and further corroborated by the pGmWIPs::GUS reporter system. These findings suggest that <i>GmWIP</i> genes may act as regulators in the defense responses of susceptible soybean cultivars, providing a foundation for future functional studies.
ISSN:2073-4395