Prediction of Extrathyroidal Extension Using Ultrasonography and Computed Tomography
Objectives. The aim of the present study was to evaluate the value of high-resolution ultrasound (US) and computed tomography (CT) scan for preoperative prediction of the extrathyroidal extension (ETE). Methods. We analyzed the medical records of 377 patients with papillary thyroid carcinoma (PTC) w...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2014-01-01
|
| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2014/351058 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832564466218172416 |
|---|---|
| author | Doh Young Lee Tack-Kyun Kwon Myung-Whun Sung Kwang Hyun Kim J. Hun Hah |
| author_facet | Doh Young Lee Tack-Kyun Kwon Myung-Whun Sung Kwang Hyun Kim J. Hun Hah |
| author_sort | Doh Young Lee |
| collection | DOAJ |
| description | Objectives. The aim of the present study was to evaluate the value of high-resolution ultrasound (US) and computed tomography (CT) scan for preoperative prediction of the extrathyroidal extension (ETE). Methods. We analyzed the medical records of 377 patients with papillary thyroid carcinoma (PTC) with preoperative US and CT scan to calculate the sensitivity, specificity, and positive and negative predictive values of characteristics imaging features (such as contact and disruption of thyroid capsule) for the presence of ETE in postoperative pathologic examination. We also evaluated the diagnostic power for several combinations of US and CT findings. Results. ETE was present in 174 (46.2%) based on pathologic reports. The frequency of ETE was greater in the patients with greater degrees of tumor contact and disruption of capsule, as revealed by both US and CT scans (positive predictive value of 72.2% and 81.8%, resp.). Considering positive predictive values and AUC of US and CT categories, separately or combined, a combination of US and CT findings was most accurate for predicting ETE (83.0%, 0.744). Conclusions. This study suggests that ETE can be predicted most accurately by a combination of categories based on the findings of US and CT scans. |
| format | Article |
| id | doaj-art-49a4ee91556e4433bd9d5a4cffbc11d3 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-49a4ee91556e4433bd9d5a4cffbc11d32025-02-03T01:11:00ZengWileyInternational Journal of Endocrinology1687-83371687-83452014-01-01201410.1155/2014/351058351058Prediction of Extrathyroidal Extension Using Ultrasonography and Computed TomographyDoh Young Lee0Tack-Kyun Kwon1Myung-Whun Sung2Kwang Hyun Kim3J. Hun Hah4Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-Ro, Jongno-Gu, Seoul 110-744, Republic of KoreaDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-Ro, Jongno-Gu, Seoul 110-744, Republic of KoreaDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-Ro, Jongno-Gu, Seoul 110-744, Republic of KoreaDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-Ro, Jongno-Gu, Seoul 110-744, Republic of KoreaDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, 101 Daehak-Ro, Jongno-Gu, Seoul 110-744, Republic of KoreaObjectives. The aim of the present study was to evaluate the value of high-resolution ultrasound (US) and computed tomography (CT) scan for preoperative prediction of the extrathyroidal extension (ETE). Methods. We analyzed the medical records of 377 patients with papillary thyroid carcinoma (PTC) with preoperative US and CT scan to calculate the sensitivity, specificity, and positive and negative predictive values of characteristics imaging features (such as contact and disruption of thyroid capsule) for the presence of ETE in postoperative pathologic examination. We also evaluated the diagnostic power for several combinations of US and CT findings. Results. ETE was present in 174 (46.2%) based on pathologic reports. The frequency of ETE was greater in the patients with greater degrees of tumor contact and disruption of capsule, as revealed by both US and CT scans (positive predictive value of 72.2% and 81.8%, resp.). Considering positive predictive values and AUC of US and CT categories, separately or combined, a combination of US and CT findings was most accurate for predicting ETE (83.0%, 0.744). Conclusions. This study suggests that ETE can be predicted most accurately by a combination of categories based on the findings of US and CT scans.http://dx.doi.org/10.1155/2014/351058 |
| spellingShingle | Doh Young Lee Tack-Kyun Kwon Myung-Whun Sung Kwang Hyun Kim J. Hun Hah Prediction of Extrathyroidal Extension Using Ultrasonography and Computed Tomography International Journal of Endocrinology |
| title | Prediction of Extrathyroidal Extension Using Ultrasonography and Computed Tomography |
| title_full | Prediction of Extrathyroidal Extension Using Ultrasonography and Computed Tomography |
| title_fullStr | Prediction of Extrathyroidal Extension Using Ultrasonography and Computed Tomography |
| title_full_unstemmed | Prediction of Extrathyroidal Extension Using Ultrasonography and Computed Tomography |
| title_short | Prediction of Extrathyroidal Extension Using Ultrasonography and Computed Tomography |
| title_sort | prediction of extrathyroidal extension using ultrasonography and computed tomography |
| url | http://dx.doi.org/10.1155/2014/351058 |
| work_keys_str_mv | AT dohyounglee predictionofextrathyroidalextensionusingultrasonographyandcomputedtomography AT tackkyunkwon predictionofextrathyroidalextensionusingultrasonographyandcomputedtomography AT myungwhunsung predictionofextrathyroidalextensionusingultrasonographyandcomputedtomography AT kwanghyunkim predictionofextrathyroidalextensionusingultrasonographyandcomputedtomography AT jhunhah predictionofextrathyroidalextensionusingultrasonographyandcomputedtomography |