Short- and long-term prognosis in patients with unstable angina and anemia

Aim. To investigate correlation between anemia and long- and short-term prognosis in patients with unstable angina. Material and methods. The study included 96 patients (34 females), aged 63.3±10.3 years, with unstable angina. All patients received conservative treatment. Individuals with severe ass...

Full description

Saved in:
Bibliographic Details
Main Authors: T. Yu. Kalyuta, O. E. Tsareva, A. D. Trubetskov, Yu. G. Schwarz
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2005-04-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/930
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849250459529773056
author T. Yu. Kalyuta
O. E. Tsareva
A. D. Trubetskov
Yu. G. Schwarz
author_facet T. Yu. Kalyuta
O. E. Tsareva
A. D. Trubetskov
Yu. G. Schwarz
author_sort T. Yu. Kalyuta
collection DOAJ
description Aim. To investigate correlation between anemia and long- and short-term prognosis in patients with unstable angina. Material and methods. The study included 96 patients (34 females), aged 63.3±10.3 years, with unstable angina. All patients received conservative treatment. Individuals with severe associated pathology and hemorrhages in anamnesis were excluded from the study. Anemia was diagnosed according to WHO criteria; unstable angina class was registered. Short-term, in-hospital prognosis assessment included registering severe, recurrent angina, myocardial infarction (MI), number of ischemic episodes during 24-hour ECG monitoring before discharge. Long-term prognosis was assessed during 6 post-discharge months: death, MI, and combined endpoint (cardiac death, MI, recurrent angina) were registered. Results. Anemia was diagnosed in 38 patients (39.58 %). Angina at rest was associated with lower mean hemoglobin (Hb) level and greater anemia prevalence (46%), comparing to the group of progressing effort angina (25%). Participants with prolonged angina episodes had significantly lower Hb level (122.23±13.3 g/l) than the others (130.9±13.56 g/l). Among patients with ischemic episodes at 24-hour ECG monitoring, anemia was registered in 50%, among individuals without such episodes – in 30.4%. Recurrent unstable angina during 6 post-discharge months was associated with higher anemia prevalence: 57.6% vs 21.05% in participants with better outcome. Logistic regression analysis demonstrated negative independent influence of anemia on combined endpoint. Conclusion. Patients with anemic syndrome were characterized by severe in-hospital course of unstable angina. Anemia was associated with increased risk of MI and recurrent unstable angina in the first 6 months after discharge.
format Article
id doaj-art-49a460cd0b3d48b3a38e1b115514d72b
institution Kabale University
issn 1728-8800
2619-0125
language Russian
publishDate 2005-04-01
publisher «SILICEA-POLIGRAF» LLC
record_format Article
series Кардиоваскулярная терапия и профилактика
spelling doaj-art-49a460cd0b3d48b3a38e1b115514d72b2025-08-20T03:57:17Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252005-04-01424651645Short- and long-term prognosis in patients with unstable angina and anemiaT. Yu. Kalyuta0O. E. Tsareva1A. D. Trubetskov2Yu. G. Schwarz3Saratov State Medical University, SaratovSaratov State Medical University, SaratovSaratov State Medical University, SaratovSaratov State Medical University, SaratovAim. To investigate correlation between anemia and long- and short-term prognosis in patients with unstable angina. Material and methods. The study included 96 patients (34 females), aged 63.3±10.3 years, with unstable angina. All patients received conservative treatment. Individuals with severe associated pathology and hemorrhages in anamnesis were excluded from the study. Anemia was diagnosed according to WHO criteria; unstable angina class was registered. Short-term, in-hospital prognosis assessment included registering severe, recurrent angina, myocardial infarction (MI), number of ischemic episodes during 24-hour ECG monitoring before discharge. Long-term prognosis was assessed during 6 post-discharge months: death, MI, and combined endpoint (cardiac death, MI, recurrent angina) were registered. Results. Anemia was diagnosed in 38 patients (39.58 %). Angina at rest was associated with lower mean hemoglobin (Hb) level and greater anemia prevalence (46%), comparing to the group of progressing effort angina (25%). Participants with prolonged angina episodes had significantly lower Hb level (122.23±13.3 g/l) than the others (130.9±13.56 g/l). Among patients with ischemic episodes at 24-hour ECG monitoring, anemia was registered in 50%, among individuals without such episodes – in 30.4%. Recurrent unstable angina during 6 post-discharge months was associated with higher anemia prevalence: 57.6% vs 21.05% in participants with better outcome. Logistic regression analysis demonstrated negative independent influence of anemia on combined endpoint. Conclusion. Patients with anemic syndrome were characterized by severe in-hospital course of unstable angina. Anemia was associated with increased risk of MI and recurrent unstable angina in the first 6 months after discharge.https://cardiovascular.elpub.ru/jour/article/view/930unstable anginaanemiahemoglobinmyocardial infarctionshort-term and long-term prognosis
spellingShingle T. Yu. Kalyuta
O. E. Tsareva
A. D. Trubetskov
Yu. G. Schwarz
Short- and long-term prognosis in patients with unstable angina and anemia
Кардиоваскулярная терапия и профилактика
unstable angina
anemia
hemoglobin
myocardial infarction
short-term and long-term prognosis
title Short- and long-term prognosis in patients with unstable angina and anemia
title_full Short- and long-term prognosis in patients with unstable angina and anemia
title_fullStr Short- and long-term prognosis in patients with unstable angina and anemia
title_full_unstemmed Short- and long-term prognosis in patients with unstable angina and anemia
title_short Short- and long-term prognosis in patients with unstable angina and anemia
title_sort short and long term prognosis in patients with unstable angina and anemia
topic unstable angina
anemia
hemoglobin
myocardial infarction
short-term and long-term prognosis
url https://cardiovascular.elpub.ru/jour/article/view/930
work_keys_str_mv AT tyukalyuta shortandlongtermprognosisinpatientswithunstableanginaandanemia
AT oetsareva shortandlongtermprognosisinpatientswithunstableanginaandanemia
AT adtrubetskov shortandlongtermprognosisinpatientswithunstableanginaandanemia
AT yugschwarz shortandlongtermprognosisinpatientswithunstableanginaandanemia