Heparan sulphate inhibition of cell proliferation induced by TGFβ and PDGF
The effect of glycosaminoglycans (GAGs) on the proliferation of smooth muscle cells (SMC) and fibroblasts was assessed by culturing cells with or without GAGs. Porcine heparan sulphate (HS) inhibited proliferation in a dose dependent manner. At 167 μg/ml of HS this reached 88% and 72% inhibition of...
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Main Authors: | lan E. Silber, Jeanine M. Walenga, Jawed Fareed, Elizabeth J. Kovacs |
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Format: | Article |
Language: | English |
Published: |
Wiley
1993-01-01
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Series: | Mediators of Inflammation |
Online Access: | http://dx.doi.org/10.1155/S0962935193000419 |
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