Concurrent Malignant Solitary Fibrous Tumor Arising from the Omentum and Grade 3 Endometrial Endometrioid Adenocarcinoma of the Uterus with p53 Immunoreactivity
A malignant solitary fibrous tumor arising from the omentum is extremely rare. To our knowledge, this is the first case of a malignant solitary fibrous omentum tumor coexisting with uterine corpus cancer. A 62-year-old woman presented to our hospital with vaginal discharge. Endometrioid adenocarcino...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2014/216340 |
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| author | Naoya Harada Ichiro Nobuhara Noriko Haruta Yumi Higashiura Hideki Watanabe Sumire Ohno |
| author_facet | Naoya Harada Ichiro Nobuhara Noriko Haruta Yumi Higashiura Hideki Watanabe Sumire Ohno |
| author_sort | Naoya Harada |
| collection | DOAJ |
| description | A malignant solitary fibrous tumor arising from the omentum is extremely rare. To our knowledge, this is the first case of a malignant solitary fibrous omentum tumor coexisting with uterine corpus cancer. A 62-year-old woman presented to our hospital with vaginal discharge. Endometrioid adenocarcinoma was diagnosed by endometrial curettage. In addition, a solid tumor in front of the uterus was detected following computed tomography and/or magnetic resonance imaging, which was suspected to be a primary (or secondary) malignant tumor arising from the omentum. Hysterectomy, bilateral salpingo-oophorectomy, omentectomy, and lymphadenectomy were performed. A malignant solitary fibrous tumor of the omentum and grade 3 endometrioid adenocarcinoma of the uterus were diagnosed by pathohistological analysis. Interestingly, the tumor cells were immunoreactive for p53. Adjuvant chemotherapy was administered for the uterine corpus cancer and the patient remains healthy 48 months after the surgery. These tumors may have become malignant due to the presence of p53 mutations. |
| format | Article |
| id | doaj-art-497120ea4f7042fabcdaf4eb020f41b0 |
| institution | Kabale University |
| issn | 2090-6684 2090-6692 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj-art-497120ea4f7042fabcdaf4eb020f41b02025-02-03T01:00:52ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922014-01-01201410.1155/2014/216340216340Concurrent Malignant Solitary Fibrous Tumor Arising from the Omentum and Grade 3 Endometrial Endometrioid Adenocarcinoma of the Uterus with p53 ImmunoreactivityNaoya Harada0Ichiro Nobuhara1Noriko Haruta2Yumi Higashiura3Hideki Watanabe4Sumire Ohno5Department of Obstetrics and Gynecology, Nara City Hospital, 1-50-1 Higashikidera-cho, Nara, Nara Prefecture 630-8305, JapanDepartment of Obstetrics and Gynecology, Nara City Hospital, 1-50-1 Higashikidera-cho, Nara, Nara Prefecture 630-8305, JapanDepartment of Obstetrics and Gynecology, Nara City Hospital, 1-50-1 Higashikidera-cho, Nara, Nara Prefecture 630-8305, JapanDepartment of Obstetrics and Gynecology, Nara City Hospital, 1-50-1 Higashikidera-cho, Nara, Nara Prefecture 630-8305, JapanDepartment of Obstetrics and Gynecology, Nara City Hospital, 1-50-1 Higashikidera-cho, Nara, Nara Prefecture 630-8305, JapanDepartment of Obstetrics and Gynecology, Nara City Hospital, 1-50-1 Higashikidera-cho, Nara, Nara Prefecture 630-8305, JapanA malignant solitary fibrous tumor arising from the omentum is extremely rare. To our knowledge, this is the first case of a malignant solitary fibrous omentum tumor coexisting with uterine corpus cancer. A 62-year-old woman presented to our hospital with vaginal discharge. Endometrioid adenocarcinoma was diagnosed by endometrial curettage. In addition, a solid tumor in front of the uterus was detected following computed tomography and/or magnetic resonance imaging, which was suspected to be a primary (or secondary) malignant tumor arising from the omentum. Hysterectomy, bilateral salpingo-oophorectomy, omentectomy, and lymphadenectomy were performed. A malignant solitary fibrous tumor of the omentum and grade 3 endometrioid adenocarcinoma of the uterus were diagnosed by pathohistological analysis. Interestingly, the tumor cells were immunoreactive for p53. Adjuvant chemotherapy was administered for the uterine corpus cancer and the patient remains healthy 48 months after the surgery. These tumors may have become malignant due to the presence of p53 mutations.http://dx.doi.org/10.1155/2014/216340 |
| spellingShingle | Naoya Harada Ichiro Nobuhara Noriko Haruta Yumi Higashiura Hideki Watanabe Sumire Ohno Concurrent Malignant Solitary Fibrous Tumor Arising from the Omentum and Grade 3 Endometrial Endometrioid Adenocarcinoma of the Uterus with p53 Immunoreactivity Case Reports in Obstetrics and Gynecology |
| title | Concurrent Malignant Solitary Fibrous Tumor Arising from the Omentum and Grade 3 Endometrial Endometrioid Adenocarcinoma of the Uterus with p53 Immunoreactivity |
| title_full | Concurrent Malignant Solitary Fibrous Tumor Arising from the Omentum and Grade 3 Endometrial Endometrioid Adenocarcinoma of the Uterus with p53 Immunoreactivity |
| title_fullStr | Concurrent Malignant Solitary Fibrous Tumor Arising from the Omentum and Grade 3 Endometrial Endometrioid Adenocarcinoma of the Uterus with p53 Immunoreactivity |
| title_full_unstemmed | Concurrent Malignant Solitary Fibrous Tumor Arising from the Omentum and Grade 3 Endometrial Endometrioid Adenocarcinoma of the Uterus with p53 Immunoreactivity |
| title_short | Concurrent Malignant Solitary Fibrous Tumor Arising from the Omentum and Grade 3 Endometrial Endometrioid Adenocarcinoma of the Uterus with p53 Immunoreactivity |
| title_sort | concurrent malignant solitary fibrous tumor arising from the omentum and grade 3 endometrial endometrioid adenocarcinoma of the uterus with p53 immunoreactivity |
| url | http://dx.doi.org/10.1155/2014/216340 |
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