Latanoprost Induced Iris Pigment Epithelial and Ciliary Body Cyst Formation in Hypermetropic Eyes
Purpose. Latanoprost has become one of the most widely prescribed topical antihypertensive medications in recent years. Yet there have been few reports of secondary iris pigment epithelial (IPE) and ciliary body (CB) cyst formation to date and none, to our knowledge, reported in eyes predisposed to...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Ophthalmological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2017/9362163 |
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| author | Abhijit Anand Mohite Rangarajan V. Prabhu Thomas Ressiniotis |
| author_facet | Abhijit Anand Mohite Rangarajan V. Prabhu Thomas Ressiniotis |
| author_sort | Abhijit Anand Mohite |
| collection | DOAJ |
| description | Purpose. Latanoprost has become one of the most widely prescribed topical antihypertensive medications in recent years. Yet there have been few reports of secondary iris pigment epithelial (IPE) and ciliary body (CB) cyst formation to date and none, to our knowledge, reported in eyes predisposed to primary angle closure. Methods. We report the first documented case of bilateral IPE and CB cysts in a hypermetropic patient with prior laser peripheral iridotomies (LPIs) as a rare, delayed side effect of topical Latanoprost treatment. The cysts subsided with discontinuation of Latanoprost, thereby demonstrating a causal relationship. We discuss the pathogenesis of such cysts and advocate using of serial ultrasound biomicroscopic (UBM) images to monitor them. Results and Conclusions. Latanoprost may cause iris pigment epithelial and ciliary body cysts that remain clinically undetected. In eyes predisposed to angle closure, such cysts may become clinically detectable and masquerade as iris tumours. Prior laser peripheral iridotomies in these eyes may delay or prevent the detection of these cysts. Ultrasound biomicroscopy (UBM) imaging is therefore a valuable tool in diagnosing and monitoring these cysts. |
| format | Article |
| id | doaj-art-49666a20e93f45ae9fe39efb6325db8f |
| institution | Kabale University |
| issn | 2090-6722 2090-6730 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Ophthalmological Medicine |
| spelling | doaj-art-49666a20e93f45ae9fe39efb6325db8f2025-02-03T06:11:04ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302017-01-01201710.1155/2017/93621639362163Latanoprost Induced Iris Pigment Epithelial and Ciliary Body Cyst Formation in Hypermetropic EyesAbhijit Anand Mohite0Rangarajan V. Prabhu1Thomas Ressiniotis2Department of Ophthalmology, New Cross Hospital, The Royal Wolverhampton Hospitals NHS Trust, Wolverhampton Road, Wolverhampton WV10 0QP, UKDepartment of Ophthalmology, Good Hope Hospital, Heart of England NHS Foundation Trust, Rectory Road, Sutton Coldfield B75 7RR, UKDepartment of Ophthalmology, Good Hope Hospital, Heart of England NHS Foundation Trust, Rectory Road, Sutton Coldfield B75 7RR, UKPurpose. Latanoprost has become one of the most widely prescribed topical antihypertensive medications in recent years. Yet there have been few reports of secondary iris pigment epithelial (IPE) and ciliary body (CB) cyst formation to date and none, to our knowledge, reported in eyes predisposed to primary angle closure. Methods. We report the first documented case of bilateral IPE and CB cysts in a hypermetropic patient with prior laser peripheral iridotomies (LPIs) as a rare, delayed side effect of topical Latanoprost treatment. The cysts subsided with discontinuation of Latanoprost, thereby demonstrating a causal relationship. We discuss the pathogenesis of such cysts and advocate using of serial ultrasound biomicroscopic (UBM) images to monitor them. Results and Conclusions. Latanoprost may cause iris pigment epithelial and ciliary body cysts that remain clinically undetected. In eyes predisposed to angle closure, such cysts may become clinically detectable and masquerade as iris tumours. Prior laser peripheral iridotomies in these eyes may delay or prevent the detection of these cysts. Ultrasound biomicroscopy (UBM) imaging is therefore a valuable tool in diagnosing and monitoring these cysts.http://dx.doi.org/10.1155/2017/9362163 |
| spellingShingle | Abhijit Anand Mohite Rangarajan V. Prabhu Thomas Ressiniotis Latanoprost Induced Iris Pigment Epithelial and Ciliary Body Cyst Formation in Hypermetropic Eyes Case Reports in Ophthalmological Medicine |
| title | Latanoprost Induced Iris Pigment Epithelial and Ciliary Body Cyst Formation in Hypermetropic Eyes |
| title_full | Latanoprost Induced Iris Pigment Epithelial and Ciliary Body Cyst Formation in Hypermetropic Eyes |
| title_fullStr | Latanoprost Induced Iris Pigment Epithelial and Ciliary Body Cyst Formation in Hypermetropic Eyes |
| title_full_unstemmed | Latanoprost Induced Iris Pigment Epithelial and Ciliary Body Cyst Formation in Hypermetropic Eyes |
| title_short | Latanoprost Induced Iris Pigment Epithelial and Ciliary Body Cyst Formation in Hypermetropic Eyes |
| title_sort | latanoprost induced iris pigment epithelial and ciliary body cyst formation in hypermetropic eyes |
| url | http://dx.doi.org/10.1155/2017/9362163 |
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