Chinese Skullcap in Move Free Arthritis Supplement Causes Drug Induced Liver Injury and Pulmonary Infiltrates
Herbal medications are being increasingly used by the American population especially for common conditions like arthritis. They have been reported to cause adverse effects, including significant hepatotoxicity, but reporting remains sporadic. We report here a patient who developed drug induced liver...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2013/965092 |
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| _version_ | 1832554904883822592 |
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| author | Renumathy Dhanasekaran Victoria Owens William Sanchez |
| author_facet | Renumathy Dhanasekaran Victoria Owens William Sanchez |
| author_sort | Renumathy Dhanasekaran |
| collection | DOAJ |
| description | Herbal medications are being increasingly used by the American population especially for common conditions like arthritis. They have been reported to cause adverse effects, including significant hepatotoxicity, but reporting remains sporadic. We report here a patient who developed drug induced liver injury following the intake of Move Free, which is an over-the-counter arthritis supplement. We propose that Chinese skullcap, which is one of the herbal ingredients of the medication, is responsible for the adverse event. There was a strong temporal association between the intake of supplement and onset of symptoms, and also there have been a few recent case reports implicating the same component. A unique observation in our case is the occurrence of pulmonary infiltrates simultaneously with the hepatotoxicity, and this side effect has not been well documented before. Both the hepatic and pulmonary complications completely resolved over few weeks after the patient stopped taking the medication. Since these supplements are readily available over the counter, we feel that it is important to document possible adverse outcomes to raise awareness in the medical community and also among patients. |
| format | Article |
| id | doaj-art-495e67d6fab34fde9d6d64f4829e23f4 |
| institution | Kabale University |
| issn | 2090-6587 2090-6595 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hepatology |
| spelling | doaj-art-495e67d6fab34fde9d6d64f4829e23f42025-02-03T05:50:10ZengWileyCase Reports in Hepatology2090-65872090-65952013-01-01201310.1155/2013/965092965092Chinese Skullcap in Move Free Arthritis Supplement Causes Drug Induced Liver Injury and Pulmonary InfiltratesRenumathy Dhanasekaran0Victoria Owens1William Sanchez2Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USADepartment of Pathology, Mayo Clinic, Rochester, MN 55905, USADivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USAHerbal medications are being increasingly used by the American population especially for common conditions like arthritis. They have been reported to cause adverse effects, including significant hepatotoxicity, but reporting remains sporadic. We report here a patient who developed drug induced liver injury following the intake of Move Free, which is an over-the-counter arthritis supplement. We propose that Chinese skullcap, which is one of the herbal ingredients of the medication, is responsible for the adverse event. There was a strong temporal association between the intake of supplement and onset of symptoms, and also there have been a few recent case reports implicating the same component. A unique observation in our case is the occurrence of pulmonary infiltrates simultaneously with the hepatotoxicity, and this side effect has not been well documented before. Both the hepatic and pulmonary complications completely resolved over few weeks after the patient stopped taking the medication. Since these supplements are readily available over the counter, we feel that it is important to document possible adverse outcomes to raise awareness in the medical community and also among patients.http://dx.doi.org/10.1155/2013/965092 |
| spellingShingle | Renumathy Dhanasekaran Victoria Owens William Sanchez Chinese Skullcap in Move Free Arthritis Supplement Causes Drug Induced Liver Injury and Pulmonary Infiltrates Case Reports in Hepatology |
| title | Chinese Skullcap in Move Free Arthritis Supplement Causes Drug Induced Liver Injury and Pulmonary Infiltrates |
| title_full | Chinese Skullcap in Move Free Arthritis Supplement Causes Drug Induced Liver Injury and Pulmonary Infiltrates |
| title_fullStr | Chinese Skullcap in Move Free Arthritis Supplement Causes Drug Induced Liver Injury and Pulmonary Infiltrates |
| title_full_unstemmed | Chinese Skullcap in Move Free Arthritis Supplement Causes Drug Induced Liver Injury and Pulmonary Infiltrates |
| title_short | Chinese Skullcap in Move Free Arthritis Supplement Causes Drug Induced Liver Injury and Pulmonary Infiltrates |
| title_sort | chinese skullcap in move free arthritis supplement causes drug induced liver injury and pulmonary infiltrates |
| url | http://dx.doi.org/10.1155/2013/965092 |
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