Insights from the single-cell level: lineage trajectory and somatic-germline interactions during spermatogenesis in dwarf surfclam Mulinia lateralis

Insights from the single-cell level: lineage trajectory and somatic-germline interactions during spermatogenesis in dwarf surfclam Mulinia lateralis

Abstract Background Spermatogenesis is a complex process of cellular differentiation that commences with the division of spermatogonia stem cells, ultimately resulting in the production of functional spermatozoa. However, a substantial gap remains in our understanding of the molecular mechanisms and...

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Bibliographic Details
Main Authors: Yajuan Li, Huilan Wei, Xiaoting Dai, Lijing Zhang, Liangjie Liu, Xiaomei Chen, Tian Liu, Ya Shu, Yaxin Yang, Shi Wang, Zhenmin Bao, Lingling Zhang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Genomics
Subjects:
Testis
Spermatogenesis
scRNA-seq
WGCNA
Gonadal niche
Mulinia lateralis
Online Access:https://doi.org/10.1186/s12864-025-11266-w
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