EGFR-Mutant Lung Adenocarcinoma Mimicking a Pneumonia
PET-CT scan has demonstrated to be very effective in lung cancer diagnosis and staging, but lung cancer has multiple ways of presentation, which can lead to an error in diagnosis imaging and a delay on the beginning of specific treatment. We present a case of a 77-year-old man with an initial PET-CT...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Pulmonology |
| Online Access: | http://dx.doi.org/10.1155/2012/257827 |
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| _version_ | 1832567933348347904 |
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| author | Álvaro Taus Flavio Zuccarino Carlos Trampal Edurne Arriola |
| author_facet | Álvaro Taus Flavio Zuccarino Carlos Trampal Edurne Arriola |
| author_sort | Álvaro Taus |
| collection | DOAJ |
| description | PET-CT scan has demonstrated to be very effective in lung cancer diagnosis and staging, but lung cancer has multiple ways of presentation, which can lead to an error in diagnosis imaging and a delay on the beginning of specific treatment. We present a case of a 77-year-old man with an initial PET-CT scan showing high 18F-FDG intake, suggesting a bilateral pneumonia, who was finally diagnosed of an EGFR-mutant lung adenocarcinoma. EGFR-activating mutation allowed us to start treatment with the oral tyrosin kinase inhibitor Gefitinib, obtaining a rapid and sustained response. Histological confirmation of imaging findings is always necessary to avoid diagnostic errors. |
| format | Article |
| id | doaj-art-491fbabed6b0476e8c4ddca5963cd79b |
| institution | Kabale University |
| issn | 2090-6846 2090-6854 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pulmonology |
| spelling | doaj-art-491fbabed6b0476e8c4ddca5963cd79b2025-02-03T01:00:03ZengWileyCase Reports in Pulmonology2090-68462090-68542012-01-01201210.1155/2012/257827257827EGFR-Mutant Lung Adenocarcinoma Mimicking a PneumoniaÁlvaro Taus0Flavio Zuccarino1Carlos Trampal2Edurne Arriola3Medical Oncology Department, Hospital del Mar-Parc de Salut Mar, Passeig Maritim 25-29, 08003 Barcelona, SpainRadiology Department, IDIMAS-CRC, Hospital del Mar, Passeig Maritim 25-29, 08003 Barcelona, SpainPET Unit Molecular Imaging Center, CRC CIM-CRC Mar, Passeig Maritim 25-29, 08003 Barcelona, SpainMedical Oncology Department, Hospital del Mar-Parc de Salut Mar, Passeig Maritim 25-29, 08003 Barcelona, SpainPET-CT scan has demonstrated to be very effective in lung cancer diagnosis and staging, but lung cancer has multiple ways of presentation, which can lead to an error in diagnosis imaging and a delay on the beginning of specific treatment. We present a case of a 77-year-old man with an initial PET-CT scan showing high 18F-FDG intake, suggesting a bilateral pneumonia, who was finally diagnosed of an EGFR-mutant lung adenocarcinoma. EGFR-activating mutation allowed us to start treatment with the oral tyrosin kinase inhibitor Gefitinib, obtaining a rapid and sustained response. Histological confirmation of imaging findings is always necessary to avoid diagnostic errors.http://dx.doi.org/10.1155/2012/257827 |
| spellingShingle | Álvaro Taus Flavio Zuccarino Carlos Trampal Edurne Arriola EGFR-Mutant Lung Adenocarcinoma Mimicking a Pneumonia Case Reports in Pulmonology |
| title | EGFR-Mutant Lung Adenocarcinoma Mimicking a Pneumonia |
| title_full | EGFR-Mutant Lung Adenocarcinoma Mimicking a Pneumonia |
| title_fullStr | EGFR-Mutant Lung Adenocarcinoma Mimicking a Pneumonia |
| title_full_unstemmed | EGFR-Mutant Lung Adenocarcinoma Mimicking a Pneumonia |
| title_short | EGFR-Mutant Lung Adenocarcinoma Mimicking a Pneumonia |
| title_sort | egfr mutant lung adenocarcinoma mimicking a pneumonia |
| url | http://dx.doi.org/10.1155/2012/257827 |
| work_keys_str_mv | AT alvarotaus egfrmutantlungadenocarcinomamimickingapneumonia AT flaviozuccarino egfrmutantlungadenocarcinomamimickingapneumonia AT carlostrampal egfrmutantlungadenocarcinomamimickingapneumonia AT edurnearriola egfrmutantlungadenocarcinomamimickingapneumonia |