LRMAHpan: a novel tool for multi-allelic HLA presentation prediction using Resnet-based and LSTM-based neural networks

LRMAHpan: a novel tool for multi-allelic HLA presentation prediction using Resnet-based and LSTM-based neural networks

IntroductionThe identification of peptides eluted from HLA complexes by mass spectrometry (MS) can provide critical data for deep learning models of antigen presentation prediction and promote neoantigen vaccine design. A major challenge remains in determining which HLA allele eluted peptides corres...

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Bibliographic Details
Main Authors: Xue Mi, Shaohao Li, Zheng Ye, Zhu Dai, Bo Ding, Bo Sun, Yang Shen, Zhongdang Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Immunology
Subjects:
biomedical engineering
neoantigen prediction
deep learning
multi allelic HLA
MHC
antigen processing
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1478201/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1478201/full

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