Cutaneous Squamous Cell Carcinoma of the Head and Neck
Cutaneous squamous cell carcinoma of the head and neck is an epidemic that reaches all parts of the world. Making the diagnosis relies on the acumen of the clinician and pathologist. Various pathologic subtypes exist and differ in histology and prognosis. High-risk tumors need aggressive treatment a...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Journal of Skin Cancer |
| Online Access: | http://dx.doi.org/10.1155/2011/502723 |
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| _version_ | 1832551605412560896 |
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| author | Vivek V. Gurudutt Eric M. Genden |
| author_facet | Vivek V. Gurudutt Eric M. Genden |
| author_sort | Vivek V. Gurudutt |
| collection | DOAJ |
| description | Cutaneous squamous cell carcinoma of the head and neck is an epidemic that reaches all parts of the world. Making the diagnosis relies on the acumen of the clinician and pathologist. Various pathologic subtypes exist and differ in histology and prognosis. High-risk tumors need aggressive treatment and vigilant surveillance to monitor for recurrence. Large tumors, deep tissue invasion, perineural involvement, recurrence, location in high-risk areas, and immunosuppression are implicated in worsening prognosis. Surgery is the mainstay of treatment with adjuvant radiation therapy as needed for aggressive tumors; however, other modalities are potentially useful for low-risk lesions. The use of Mohs surgery has become increasingly useful and has shown high success rates. Involvement of parotid and neck lymph nodes significantly affects outcomes and the physician should be comfortable with management of this complex disease. This paper examines the diagnosis, pathology, clinical course, and treatment options for cutaneous squamous cell carcinoma of the head and neck. |
| format | Article |
| id | doaj-art-490ac2e89baa4673afe2c0cd02cb56e2 |
| institution | Kabale University |
| issn | 2090-2905 2090-2913 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Skin Cancer |
| spelling | doaj-art-490ac2e89baa4673afe2c0cd02cb56e22025-02-03T06:00:57ZengWileyJournal of Skin Cancer2090-29052090-29132011-01-01201110.1155/2011/502723502723Cutaneous Squamous Cell Carcinoma of the Head and NeckVivek V. Gurudutt0Eric M. Genden1Department of Otolaryngology–Head and Neck Surgery, Mount Sinai School of Medicine, 5 East 98th Street, 8th Floor, New York, NY 10029, USADepartment of Otolaryngology–Head and Neck Surgery, Mount Sinai School of Medicine, 5 East 98th Street, 8th Floor, New York, NY 10029, USACutaneous squamous cell carcinoma of the head and neck is an epidemic that reaches all parts of the world. Making the diagnosis relies on the acumen of the clinician and pathologist. Various pathologic subtypes exist and differ in histology and prognosis. High-risk tumors need aggressive treatment and vigilant surveillance to monitor for recurrence. Large tumors, deep tissue invasion, perineural involvement, recurrence, location in high-risk areas, and immunosuppression are implicated in worsening prognosis. Surgery is the mainstay of treatment with adjuvant radiation therapy as needed for aggressive tumors; however, other modalities are potentially useful for low-risk lesions. The use of Mohs surgery has become increasingly useful and has shown high success rates. Involvement of parotid and neck lymph nodes significantly affects outcomes and the physician should be comfortable with management of this complex disease. This paper examines the diagnosis, pathology, clinical course, and treatment options for cutaneous squamous cell carcinoma of the head and neck.http://dx.doi.org/10.1155/2011/502723 |
| spellingShingle | Vivek V. Gurudutt Eric M. Genden Cutaneous Squamous Cell Carcinoma of the Head and Neck Journal of Skin Cancer |
| title | Cutaneous Squamous Cell Carcinoma of the Head and Neck |
| title_full | Cutaneous Squamous Cell Carcinoma of the Head and Neck |
| title_fullStr | Cutaneous Squamous Cell Carcinoma of the Head and Neck |
| title_full_unstemmed | Cutaneous Squamous Cell Carcinoma of the Head and Neck |
| title_short | Cutaneous Squamous Cell Carcinoma of the Head and Neck |
| title_sort | cutaneous squamous cell carcinoma of the head and neck |
| url | http://dx.doi.org/10.1155/2011/502723 |
| work_keys_str_mv | AT vivekvgurudutt cutaneoussquamouscellcarcinomaoftheheadandneck AT ericmgenden cutaneoussquamouscellcarcinomaoftheheadandneck |