Histopathological Study of Bee Venom with Different Concentrations in Laboratory Mice
Bee venom (BV) of Apis mellifer L has recently been utilized as a traditional medicine for treating a variety of medical conditions. When mice were given different concentrations of bee venom, it was found to be effective in repairing some histopathological changes. Then, when applying BV as a trea...
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| Language: | English |
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middle technical university
2021-12-01
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| Series: | Journal of Techniques |
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| Online Access: | https://journal.mtu.edu.iq/index.php/MTU/article/view/389 |
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| author | Zeyad G. Al-Rikabi Montaha Abdulkareem Al-Saffar Huda S. Nassir Inam B. Falih |
| author_facet | Zeyad G. Al-Rikabi Montaha Abdulkareem Al-Saffar Huda S. Nassir Inam B. Falih |
| author_sort | Zeyad G. Al-Rikabi |
| collection | DOAJ |
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Bee venom (BV) of Apis mellifer L has recently been utilized as a traditional medicine for treating a variety of medical conditions. When mice were given different concentrations of bee venom, it was found to be effective in repairing some histopathological changes. Then, when applying BV as a treatment material for some disorders, as indicated by the amount of damage to the liver and kidney tissues. The animals were randomly divided into 7 groups. Six of which were treated with BV extraction, and one group was designated as the control group, was treated with distilled water. Mice were injected intraperitoneally by 0.2ml of BV extraction in concentrations (1000, 750, 500, 350, 300, and 250) μg/ml. In some cases, histopathological studies revealed mild to moderate alterations in the liver and renal tissues, characterized by congestion, acute cell swelling, and focal coagulated necrosis. Atherosclerotic changes in the aorta and some arteries were found in two groups. Whereas several mild degenerative changes were observed in hepatic cells of one group. In conclusion, bee venom administered to groups in different concentrations revealed hepatic and renal complications at histological investigations of hematoxylin and eosin-stained sections of liver and kidney section.
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| format | Article |
| id | doaj-art-4909d3a44f3b42379cb5e68cf3225bc5 |
| institution | Kabale University |
| issn | 1818-653X 2708-8383 |
| language | English |
| publishDate | 2021-12-01 |
| publisher | middle technical university |
| record_format | Article |
| series | Journal of Techniques |
| spelling | doaj-art-4909d3a44f3b42379cb5e68cf3225bc52025-01-19T11:07:21Zengmiddle technical universityJournal of Techniques1818-653X2708-83832021-12-013410.51173/jt.v3i4.389Histopathological Study of Bee Venom with Different Concentrations in Laboratory MiceZeyad G. Al-Rikabi0Montaha Abdulkareem Al-Saffar1Huda S. Nassir2Inam B. Falih3Ministry of Science and Technology, Environment and Water Directorate, Baghdad / Iraq.Department of Community Health, Medical Technical Institute- Baghdad, Middle Technical University, Baghdad, IraqMinistry of Science and Technology, Environment and Water Directorate, Baghdad / Iraq.College of Veterinary Medicine, University of Baghdad, Baghdad / Iraq Bee venom (BV) of Apis mellifer L has recently been utilized as a traditional medicine for treating a variety of medical conditions. When mice were given different concentrations of bee venom, it was found to be effective in repairing some histopathological changes. Then, when applying BV as a treatment material for some disorders, as indicated by the amount of damage to the liver and kidney tissues. The animals were randomly divided into 7 groups. Six of which were treated with BV extraction, and one group was designated as the control group, was treated with distilled water. Mice were injected intraperitoneally by 0.2ml of BV extraction in concentrations (1000, 750, 500, 350, 300, and 250) μg/ml. In some cases, histopathological studies revealed mild to moderate alterations in the liver and renal tissues, characterized by congestion, acute cell swelling, and focal coagulated necrosis. Atherosclerotic changes in the aorta and some arteries were found in two groups. Whereas several mild degenerative changes were observed in hepatic cells of one group. In conclusion, bee venom administered to groups in different concentrations revealed hepatic and renal complications at histological investigations of hematoxylin and eosin-stained sections of liver and kidney section. https://journal.mtu.edu.iq/index.php/MTU/article/view/389KidneyLiverMelittinHistopathologyBee Venom |
| spellingShingle | Zeyad G. Al-Rikabi Montaha Abdulkareem Al-Saffar Huda S. Nassir Inam B. Falih Histopathological Study of Bee Venom with Different Concentrations in Laboratory Mice Journal of Techniques Kidney Liver Melittin Histopathology Bee Venom |
| title | Histopathological Study of Bee Venom with Different Concentrations in Laboratory Mice |
| title_full | Histopathological Study of Bee Venom with Different Concentrations in Laboratory Mice |
| title_fullStr | Histopathological Study of Bee Venom with Different Concentrations in Laboratory Mice |
| title_full_unstemmed | Histopathological Study of Bee Venom with Different Concentrations in Laboratory Mice |
| title_short | Histopathological Study of Bee Venom with Different Concentrations in Laboratory Mice |
| title_sort | histopathological study of bee venom with different concentrations in laboratory mice |
| topic | Kidney Liver Melittin Histopathology Bee Venom |
| url | https://journal.mtu.edu.iq/index.php/MTU/article/view/389 |
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