A phase 2, double-blind, placebo-controlled trial of a valproate/lithium combination in ALS patients

Background: Few treatments are currently available for amyotrophic lateral sclerosis (ALS). A combination of lithium carbonate and valproic acid (VPA-Li) was shown to inhibit motor neuron death and delay disease progression. Methods: Outpatients with a typical ALS presentation were enrolled in a ran...

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Bibliographic Details
Main Authors: M.-C. Boll, M. Alcaraz-Zubeldia, C. Rios, D. González-Esquivel, S. Montes
Format: Article
Language:English
Published: Elsevier España 2025-01-01
Series:Neurología (English Edition)
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Online Access:http://www.sciencedirect.com/science/article/pii/S217358082200089X
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