Erectile and Sexual Function Determinants in Men with Type 1 Diabetes

Background/Objectives: The association between sexual dysfunctions and diabetes is largely known, but few studies investigated its prevalence in Type 1 Diabetes (T1D). The aim of this study was to evaluate the prevalence of sexual dysfunction in a group of men with T1D regardless of their age and to...

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Main Authors: Cristian Petolicchio, Francesco Cocchiara, Giordano Spacco, Eliana Delle Chiaie, Maria Grazia Calevo, Davide Carlo Maggi, Diego Ferone, Nicola Minuto, Marta Bassi
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Diabetology
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Online Access:https://www.mdpi.com/2673-4540/6/5/34
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author Cristian Petolicchio
Francesco Cocchiara
Giordano Spacco
Eliana Delle Chiaie
Maria Grazia Calevo
Davide Carlo Maggi
Diego Ferone
Nicola Minuto
Marta Bassi
author_facet Cristian Petolicchio
Francesco Cocchiara
Giordano Spacco
Eliana Delle Chiaie
Maria Grazia Calevo
Davide Carlo Maggi
Diego Ferone
Nicola Minuto
Marta Bassi
author_sort Cristian Petolicchio
collection DOAJ
description Background/Objectives: The association between sexual dysfunctions and diabetes is largely known, but few studies investigated its prevalence in Type 1 Diabetes (T1D). The aim of this study was to evaluate the prevalence of sexual dysfunction in a group of men with T1D regardless of their age and to compare the prevalence in men treated with different intensive insulin regimens. Methods: The study population included 68 men affected by T1D, of whom 17 were on Multiple Daily Injections (MDI) and 51 were on Continuous Subcutaneous Insulin Infusion (41 on Advanced Hybrid Closed Loop System with catheters and 10 on patch pumps). All participants completed the International Index of Erectile Function (IIEF-15), which evaluates several domains of sexual function. Another questionnaire that evaluated general features, diabetes-specific features, and sexual-specific features was proposed to every participant. Results: The overall prevalence of erectile dysfunction was 48.5%, and the overall prevalence of a severe grade of erectile dysfunction was 26.5%. Correlations were demonstrated between the prevalence of erectile dysfunction and age and between the prevalence of erectile dysfunction and dyadic status. Age and dyadic status were also correlated with lower scores in several other domains of the IIEF-15 questionnaire. Conclusions: Men with Type 1 Diabetes present a high prevalence of erectile dysfunction, independent of glycometabolic control of the disease and insulin regimens; on the contrary, a great correlation is demonstrated with age and dyadic status.
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spelling doaj-art-48c6e61d28b547538cf815ab3ae7682e2025-08-20T01:56:19ZengMDPI AGDiabetology2673-45402025-04-01653410.3390/diabetology6050034Erectile and Sexual Function Determinants in Men with Type 1 DiabetesCristian Petolicchio0Francesco Cocchiara1Giordano Spacco2Eliana Delle Chiaie3Maria Grazia Calevo4Davide Carlo Maggi5Diego Ferone6Nicola Minuto7Marta Bassi8Endocrinology Unit, Department of Internal Medicine and Medical Specialties (DiMI), University of Genova, 16126 Genoa, ItalyEndocrinology Unit, IRCCS Ospedale Policlinico San Martino, 16126 Genoa, ItalyDINOGMI-Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, 16126 Genoa, ItalyEndocrinology Unit, Department of Internal Medicine and Medical Specialties (DiMI), University of Genova, 16126 Genoa, ItalyBiostatistic Unit, Scientific Direction, IRCCS Istituto Giannina Gaslini, 16147 Genoa, ItalyEndocrinology Unit, Department of Internal Medicine and Medical Specialties (DiMI), University of Genova, 16126 Genoa, ItalyEndocrinology Unit, Department of Internal Medicine and Medical Specialties (DiMI), University of Genova, 16126 Genoa, ItalyPediatric Clinic and Endocrinology Unit, IRCCS Istituto Giannina Gaslini, 16147 Genoa, ItalyDINOGMI-Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, 16126 Genoa, ItalyBackground/Objectives: The association between sexual dysfunctions and diabetes is largely known, but few studies investigated its prevalence in Type 1 Diabetes (T1D). The aim of this study was to evaluate the prevalence of sexual dysfunction in a group of men with T1D regardless of their age and to compare the prevalence in men treated with different intensive insulin regimens. Methods: The study population included 68 men affected by T1D, of whom 17 were on Multiple Daily Injections (MDI) and 51 were on Continuous Subcutaneous Insulin Infusion (41 on Advanced Hybrid Closed Loop System with catheters and 10 on patch pumps). All participants completed the International Index of Erectile Function (IIEF-15), which evaluates several domains of sexual function. Another questionnaire that evaluated general features, diabetes-specific features, and sexual-specific features was proposed to every participant. Results: The overall prevalence of erectile dysfunction was 48.5%, and the overall prevalence of a severe grade of erectile dysfunction was 26.5%. Correlations were demonstrated between the prevalence of erectile dysfunction and age and between the prevalence of erectile dysfunction and dyadic status. Age and dyadic status were also correlated with lower scores in several other domains of the IIEF-15 questionnaire. Conclusions: Men with Type 1 Diabetes present a high prevalence of erectile dysfunction, independent of glycometabolic control of the disease and insulin regimens; on the contrary, a great correlation is demonstrated with age and dyadic status.https://www.mdpi.com/2673-4540/6/5/34type 1 diabetessexual functionerectile dysfunctioninsulin regimensContinuous Subcutaneous Insulin Infusion (CSII)
spellingShingle Cristian Petolicchio
Francesco Cocchiara
Giordano Spacco
Eliana Delle Chiaie
Maria Grazia Calevo
Davide Carlo Maggi
Diego Ferone
Nicola Minuto
Marta Bassi
Erectile and Sexual Function Determinants in Men with Type 1 Diabetes
Diabetology
type 1 diabetes
sexual function
erectile dysfunction
insulin regimens
Continuous Subcutaneous Insulin Infusion (CSII)
title Erectile and Sexual Function Determinants in Men with Type 1 Diabetes
title_full Erectile and Sexual Function Determinants in Men with Type 1 Diabetes
title_fullStr Erectile and Sexual Function Determinants in Men with Type 1 Diabetes
title_full_unstemmed Erectile and Sexual Function Determinants in Men with Type 1 Diabetes
title_short Erectile and Sexual Function Determinants in Men with Type 1 Diabetes
title_sort erectile and sexual function determinants in men with type 1 diabetes
topic type 1 diabetes
sexual function
erectile dysfunction
insulin regimens
Continuous Subcutaneous Insulin Infusion (CSII)
url https://www.mdpi.com/2673-4540/6/5/34
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