Prevalence, comorbidities, and disease-related complications of rheumatoid arthritis in Colombia: a national cross-sectional study based on administrative claims data
Abstract Background To date, there has been limited exploration, particularly on a national scale, of the prevalence patterns of comorbidities and complications associated with rheumatoid arthritis (RA) in Colombia. We aimed to analyze the prevalence patterns of comorbidities and disease-related com...
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BMC
2025-01-01
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| Series: | Advances in Rheumatology |
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| Online Access: | https://doi.org/10.1186/s42358-025-00437-8 |
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| author | Kevin Maldonado-Cañón Giancarlo Buitrago Gerardo Quintana-López |
| author_facet | Kevin Maldonado-Cañón Giancarlo Buitrago Gerardo Quintana-López |
| author_sort | Kevin Maldonado-Cañón |
| collection | DOAJ |
| description | Abstract Background To date, there has been limited exploration, particularly on a national scale, of the prevalence patterns of comorbidities and complications associated with rheumatoid arthritis (RA) in Colombia. We aimed to analyze the prevalence patterns of comorbidities and disease-related complications of RA patients enrolled in Colombia’s contributory healthcare regime. Methods We performed a nationwide observational descriptive cross-sectional study using administrative claims data. We used a set of sensitive and specific electronic algorithms (i.e., a set of rules) applied to linked data based on ICD-10 codes and unique medication use codes. We compared all those algorithms with several sources, including governmental agencies and scientific literature, to identify all the known adults treated for RA. Results A total of 123,080 RA cases for 2018 were identified, corresponding to a point prevalence of 0.86 (95% CI 0.86–0.87) per 100. Compared to a non-RA reference population, hypertension (68.2 vs. 20.0%), osteoarthritis (43.6 vs. 6.1%), and osteoporosis (18.6 vs. 1.1%) provided larger standardized mean differences. Lupus (30.04; 95%CI 29.3–30.8), multiple sclerosis (7.18; 95%CI 6.6–7.8), and osteoporosis (5.57; 95%CI 5.5–5.6) provided higher age- and sex-adjusted prevalence ratios. Disease-related complications were found in 62.2% of cases. Conclusions We describe the first comprehensive assessment of the prevalence patterns of disease-related complications and comorbidities that define the RA burden of disease within a multimorbidity profile. Also, our study provides a narrower and more reliable point prevalence estimate for RA in Colombia. |
| format | Article |
| id | doaj-art-48c0e227fbbd4bb7b263e9d86ccb03dd |
| institution | Kabale University |
| issn | 2523-3106 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Advances in Rheumatology |
| spelling | doaj-art-48c0e227fbbd4bb7b263e9d86ccb03dd2025-02-02T12:48:30ZengBMCAdvances in Rheumatology2523-31062025-01-0165111110.1186/s42358-025-00437-8Prevalence, comorbidities, and disease-related complications of rheumatoid arthritis in Colombia: a national cross-sectional study based on administrative claims dataKevin Maldonado-Cañón0Giancarlo Buitrago1Gerardo Quintana-López2Reumavance Group, Department of Internal Medicine, School of Medicine, Universidad Nacional de ColombiaInstituto de Investigaciones Clínicas, Facultad de Medicina, Universidad Nacional de ColombiaReumavance Group, Department of Internal Medicine, School of Medicine, Universidad Nacional de ColombiaAbstract Background To date, there has been limited exploration, particularly on a national scale, of the prevalence patterns of comorbidities and complications associated with rheumatoid arthritis (RA) in Colombia. We aimed to analyze the prevalence patterns of comorbidities and disease-related complications of RA patients enrolled in Colombia’s contributory healthcare regime. Methods We performed a nationwide observational descriptive cross-sectional study using administrative claims data. We used a set of sensitive and specific electronic algorithms (i.e., a set of rules) applied to linked data based on ICD-10 codes and unique medication use codes. We compared all those algorithms with several sources, including governmental agencies and scientific literature, to identify all the known adults treated for RA. Results A total of 123,080 RA cases for 2018 were identified, corresponding to a point prevalence of 0.86 (95% CI 0.86–0.87) per 100. Compared to a non-RA reference population, hypertension (68.2 vs. 20.0%), osteoarthritis (43.6 vs. 6.1%), and osteoporosis (18.6 vs. 1.1%) provided larger standardized mean differences. Lupus (30.04; 95%CI 29.3–30.8), multiple sclerosis (7.18; 95%CI 6.6–7.8), and osteoporosis (5.57; 95%CI 5.5–5.6) provided higher age- and sex-adjusted prevalence ratios. Disease-related complications were found in 62.2% of cases. Conclusions We describe the first comprehensive assessment of the prevalence patterns of disease-related complications and comorbidities that define the RA burden of disease within a multimorbidity profile. Also, our study provides a narrower and more reliable point prevalence estimate for RA in Colombia.https://doi.org/10.1186/s42358-025-00437-8Latin AmericaComorbidityComplicationsPrevalenceRheumatoid arthritis |
| spellingShingle | Kevin Maldonado-Cañón Giancarlo Buitrago Gerardo Quintana-López Prevalence, comorbidities, and disease-related complications of rheumatoid arthritis in Colombia: a national cross-sectional study based on administrative claims data Advances in Rheumatology Latin America Comorbidity Complications Prevalence Rheumatoid arthritis |
| title | Prevalence, comorbidities, and disease-related complications of rheumatoid arthritis in Colombia: a national cross-sectional study based on administrative claims data |
| title_full | Prevalence, comorbidities, and disease-related complications of rheumatoid arthritis in Colombia: a national cross-sectional study based on administrative claims data |
| title_fullStr | Prevalence, comorbidities, and disease-related complications of rheumatoid arthritis in Colombia: a national cross-sectional study based on administrative claims data |
| title_full_unstemmed | Prevalence, comorbidities, and disease-related complications of rheumatoid arthritis in Colombia: a national cross-sectional study based on administrative claims data |
| title_short | Prevalence, comorbidities, and disease-related complications of rheumatoid arthritis in Colombia: a national cross-sectional study based on administrative claims data |
| title_sort | prevalence comorbidities and disease related complications of rheumatoid arthritis in colombia a national cross sectional study based on administrative claims data |
| topic | Latin America Comorbidity Complications Prevalence Rheumatoid arthritis |
| url | https://doi.org/10.1186/s42358-025-00437-8 |
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