Multimodal Imaging in an Unusual Cluster of Multiple Evanescent White Dot Syndrome
Objective. To describe an unusual cluster of multiple evanescent white dot syndrome (MEWDS) encountered within a 3-month period. Methods. This retrospective observation study is comprised of seven patients who presented with MEWDS in a 3-month period in central Israel. Data were collected from patie...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2017/7535320 |
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| author | Orly Gal-Or Ethan Priel Irit Rosenblatt Shiri Shulman Michal Kramer |
| author_facet | Orly Gal-Or Ethan Priel Irit Rosenblatt Shiri Shulman Michal Kramer |
| author_sort | Orly Gal-Or |
| collection | DOAJ |
| description | Objective. To describe an unusual cluster of multiple evanescent white dot syndrome (MEWDS) encountered within a 3-month period. Methods. This retrospective observation study is comprised of seven patients who presented with MEWDS in a 3-month period in central Israel. Data were collected from patients’ medical records on clinical, multimodal imaging, and viral serology findings. Results. Six women and one man of mean age 31.5 ± 7.2 years. Three reported a precedent viral infection. All had unilateral decreased vision. Funduscopy revealed foveal granularity. Main Imaging Findings. Hyperfluorescent spots on blue autofluorescence (BAF), hypofluorescent spots on indocyanine green angiography, dark lesions on infrared photos, and ellipsoid zone irregularities on spectral domain optical coherence tomography (SD-OCT). Resolution of the spots on BAF correlated with anatomic (SD-OCT) and visual recovery. OCT angiography performed following the convalescence stage demonstrated intact retinal and choroidal flow. Serologic findings were inconclusive. Conclusion. We report a unique cluster of MEWDS patients presented in a short period of time. SD-OCT findings of ellipsoid zone disruption in combination with other multimodal imaging modalities are outlined meticulously. Recognizing these imaging features along with high index of clinical suspicion is important for the diagnosis of MEWDS. Serologic testing might be considered in future patients. |
| format | Article |
| id | doaj-art-48463c0847f64634b36210a37790d07b |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-48463c0847f64634b36210a37790d07b2025-02-03T01:30:56ZengWileyJournal of Ophthalmology2090-004X2090-00582017-01-01201710.1155/2017/75353207535320Multimodal Imaging in an Unusual Cluster of Multiple Evanescent White Dot SyndromeOrly Gal-Or0Ethan Priel1Irit Rosenblatt2Shiri Shulman3Michal Kramer4Department of Ophthalmology, Rabin Medical Center-Beilinson Hospital, 4941492 Petach Tikva, IsraelMOR Institute for Medical Data, 5126413 Bnei Brak, IsraelDepartment of Ophthalmology, Rabin Medical Center-Beilinson Hospital, 4941492 Petach Tikva, IsraelDepartment of Ophthalmology, Tel Aviv Sourasky Medical Center, 62431 Tel Aviv, IsraelDepartment of Ophthalmology, Rabin Medical Center-Beilinson Hospital, 4941492 Petach Tikva, IsraelObjective. To describe an unusual cluster of multiple evanescent white dot syndrome (MEWDS) encountered within a 3-month period. Methods. This retrospective observation study is comprised of seven patients who presented with MEWDS in a 3-month period in central Israel. Data were collected from patients’ medical records on clinical, multimodal imaging, and viral serology findings. Results. Six women and one man of mean age 31.5 ± 7.2 years. Three reported a precedent viral infection. All had unilateral decreased vision. Funduscopy revealed foveal granularity. Main Imaging Findings. Hyperfluorescent spots on blue autofluorescence (BAF), hypofluorescent spots on indocyanine green angiography, dark lesions on infrared photos, and ellipsoid zone irregularities on spectral domain optical coherence tomography (SD-OCT). Resolution of the spots on BAF correlated with anatomic (SD-OCT) and visual recovery. OCT angiography performed following the convalescence stage demonstrated intact retinal and choroidal flow. Serologic findings were inconclusive. Conclusion. We report a unique cluster of MEWDS patients presented in a short period of time. SD-OCT findings of ellipsoid zone disruption in combination with other multimodal imaging modalities are outlined meticulously. Recognizing these imaging features along with high index of clinical suspicion is important for the diagnosis of MEWDS. Serologic testing might be considered in future patients.http://dx.doi.org/10.1155/2017/7535320 |
| spellingShingle | Orly Gal-Or Ethan Priel Irit Rosenblatt Shiri Shulman Michal Kramer Multimodal Imaging in an Unusual Cluster of Multiple Evanescent White Dot Syndrome Journal of Ophthalmology |
| title | Multimodal Imaging in an Unusual Cluster of Multiple Evanescent White Dot Syndrome |
| title_full | Multimodal Imaging in an Unusual Cluster of Multiple Evanescent White Dot Syndrome |
| title_fullStr | Multimodal Imaging in an Unusual Cluster of Multiple Evanescent White Dot Syndrome |
| title_full_unstemmed | Multimodal Imaging in an Unusual Cluster of Multiple Evanescent White Dot Syndrome |
| title_short | Multimodal Imaging in an Unusual Cluster of Multiple Evanescent White Dot Syndrome |
| title_sort | multimodal imaging in an unusual cluster of multiple evanescent white dot syndrome |
| url | http://dx.doi.org/10.1155/2017/7535320 |
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