A Rare Case of Squamous Cell Carcinoma of the Bladder Presenting as a Metastatic Right Ventricular Mass
A 74-year-old woman presented with bilateral lower extremity swelling, worsening dyspnea on exertion, and mild hemoptysis. An echocardiogram at time of admission showed a mass in the right ventricle. The pathology of a sample obtained via transvenous biopsy was consistent with squamous cell carcino...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2010/789609 |
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| author | Joanna M. Bonsall Rhome Hughes Mario Mosunjac David Harrison Habib Samady |
| author_facet | Joanna M. Bonsall Rhome Hughes Mario Mosunjac David Harrison Habib Samady |
| author_sort | Joanna M. Bonsall |
| collection | DOAJ |
| description | A 74-year-old woman presented with bilateral lower extremity swelling, worsening dyspnea on exertion, and mild hemoptysis. An echocardiogram at time of admission showed a mass in the right ventricle. The pathology of a sample obtained via transvenous biopsy was consistent with squamous cell carcinoma; no primary source could initially be identified. Severe thrombocytopenia, likely consumptive, precluded surgical intervention, so the patient underwent palliative radiation. Unfortunately, she developed fatal respiratory failure. Upon autopsy, the bladder was found to contain polyps of invasive squamous cell carcinoma, similar in morphology to the tumor mass in the heart. Her lungs contained multiple tumor emboli at different stages, which was likely the final cause of her death. Squamous cell carcinoma metastases to the endocardium are extremely rare and without defined treatment. Surgery can improve prognosis in those with primary tumors that are benign or without metastases. In those with symptomatic metastatic tumors, palliative debulking can done although generally will not improve prognosis. It is currently unknown whether radiation improves survival. In this case, irradiation did destroy a portion of the tumor as the final pathology showed extensive necrosis of the tumor; unfortunately, it did not change her symptoms and did not change the final outcome. |
| format | Article |
| id | doaj-art-48179be0d8c54692b8e11830218ba491 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-48179be0d8c54692b8e11830218ba4912025-02-03T01:02:11ZengWileyCase Reports in Medicine1687-96271687-96352010-01-01201010.1155/2010/789609789609A Rare Case of Squamous Cell Carcinoma of the Bladder Presenting as a Metastatic Right Ventricular MassJoanna M. Bonsall0Rhome Hughes1Mario Mosunjac2David Harrison3Habib Samady4Department of Medicine, Emory University School of Medicine, Atlanta, GA 30332, USADepartment of Pathology, Emory University School of Medicine, Atlanta, GA 30332, USADepartment of Pathology, Emory University School of Medicine, Atlanta, GA 30332, USADepartment of Medicine, Emory University School of Medicine, Atlanta, GA 30332, USADepartment of Medicine, Emory University School of Medicine, Atlanta, GA 30332, USAA 74-year-old woman presented with bilateral lower extremity swelling, worsening dyspnea on exertion, and mild hemoptysis. An echocardiogram at time of admission showed a mass in the right ventricle. The pathology of a sample obtained via transvenous biopsy was consistent with squamous cell carcinoma; no primary source could initially be identified. Severe thrombocytopenia, likely consumptive, precluded surgical intervention, so the patient underwent palliative radiation. Unfortunately, she developed fatal respiratory failure. Upon autopsy, the bladder was found to contain polyps of invasive squamous cell carcinoma, similar in morphology to the tumor mass in the heart. Her lungs contained multiple tumor emboli at different stages, which was likely the final cause of her death. Squamous cell carcinoma metastases to the endocardium are extremely rare and without defined treatment. Surgery can improve prognosis in those with primary tumors that are benign or without metastases. In those with symptomatic metastatic tumors, palliative debulking can done although generally will not improve prognosis. It is currently unknown whether radiation improves survival. In this case, irradiation did destroy a portion of the tumor as the final pathology showed extensive necrosis of the tumor; unfortunately, it did not change her symptoms and did not change the final outcome.http://dx.doi.org/10.1155/2010/789609 |
| spellingShingle | Joanna M. Bonsall Rhome Hughes Mario Mosunjac David Harrison Habib Samady A Rare Case of Squamous Cell Carcinoma of the Bladder Presenting as a Metastatic Right Ventricular Mass Case Reports in Medicine |
| title | A Rare Case of Squamous Cell Carcinoma of the Bladder Presenting as a Metastatic Right Ventricular Mass |
| title_full | A Rare Case of Squamous Cell Carcinoma of the Bladder Presenting as a Metastatic Right Ventricular Mass |
| title_fullStr | A Rare Case of Squamous Cell Carcinoma of the Bladder Presenting as a Metastatic Right Ventricular Mass |
| title_full_unstemmed | A Rare Case of Squamous Cell Carcinoma of the Bladder Presenting as a Metastatic Right Ventricular Mass |
| title_short | A Rare Case of Squamous Cell Carcinoma of the Bladder Presenting as a Metastatic Right Ventricular Mass |
| title_sort | rare case of squamous cell carcinoma of the bladder presenting as a metastatic right ventricular mass |
| url | http://dx.doi.org/10.1155/2010/789609 |
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