Immune-related gene risk model establishment and role of key gene FUCA1 in malignant pleural mesothelioma

Immune-related gene risk model establishment and role of key gene FUCA1 in malignant pleural mesothelioma

BackgroundMalignant pleural mesothelioma (MPM) is a rare type of tumor closely associated with asbestos exposure. Increasing evidence shows that high immuno-heterogeneity reduces the therapeutic efficacy of MPM. At present, good biomarkers to screen immunodominant populations and predict the efficac...

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Bibliographic Details
Main Authors: Lin Shi, Dongqi Yuan, Fuyi Zhu, Yuchao He, Ran Zuo, Liwei Chen, Yi Luo, Yu Wang, Dingzhi Huang, Peng Chen, Hua Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Pharmacology
Subjects:
malignant pleural mesothelioma
immune cell
machine learning
FUCA1
EMT
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1577232/full
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