Severe painful vaso-occlusive crises and mortality in a contemporary adult sickle cell anemia cohort study.

Severe painful vaso-occlusive crises and mortality in a contemporary adult sickle cell anemia cohort study.

<h4>Background</h4>Frequent painful vaso-occlusive crises (VOCs) were associated with mortality in the Cooperative Study of Sickle Cell Disease (CSSCD) over twenty years ago. Modern therapies for sickle cell anemia (SCA) like hydroxyurea are believed to have improved overall patient surv...

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Main Authors: Deepika S Darbari, Zhengyuan Wang, Minjung Kwak, Mariana Hildesheim, James Nichols, Darlene Allen, Catherine Seamon, Marlene Peters-Lawrence, Anna Conrey, Mary K Hall, Gregory J Kato, James G Taylor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0079923
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