Temperature and repeated catecholamine surges modulate regional wall motion abnormalities in a rodent takotsubo syndrome model

Temperature and repeated catecholamine surges modulate regional wall motion abnormalities in a rodent takotsubo syndrome model

Abstract Transient regional wall motion abnormalities (RWMA) after stress are a hallmark of experimental and clinical Takotsubo Syndrome (TS). The mechanisms driving RWMA remain incompletely understood. This study investigates these mechanisms in a small-animal model of TS, validating the model’s co...

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Bibliographic Details
Main Authors: Ermir Zulfaj, AmirAli Nejat, Abdulhussain Haamid, Aaron Espinosa, Ahmed Elmahdy, Tetiana Pylova, Sandeep Jha, Björn Redfors, Elmir Omerovic
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Takotsubo Syndrome
Regional Wall Motion abnormalities
Rat model
Body temperature
Echocardiography
Complication
Online Access:https://doi.org/10.1038/s41598-025-88410-9
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