Cardiac history and post-stroke depression association in Chinese stroke survivors: a cross sectional study

Abstract A substantial body of evidence indicates that stroke is a primary cause of death and disability on a global scale. The presence of post-stroke depression has been demonstrated to exert a substantial influence on the prognosis of stroke patients, underscoring the imperative for the identific...

Full description

Saved in:
Bibliographic Details
Main Authors: Longxiao Liu, Peng Qin, Jing Bai, Yupei Cheng, Jingjie Huang, Zihe Wang, Yuxing Zhang, Bangqi Wu
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-93308-7
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850201490171363328
author Longxiao Liu
Peng Qin
Jing Bai
Yupei Cheng
Jingjie Huang
Zihe Wang
Yuxing Zhang
Bangqi Wu
author_facet Longxiao Liu
Peng Qin
Jing Bai
Yupei Cheng
Jingjie Huang
Zihe Wang
Yuxing Zhang
Bangqi Wu
author_sort Longxiao Liu
collection DOAJ
description Abstract A substantial body of evidence indicates that stroke is a primary cause of death and disability on a global scale. The presence of post-stroke depression has been demonstrated to exert a substantial influence on the prognosis of stroke patients, underscoring the imperative for the identification and early prevention of post-stroke depression. The objective of this study was to examine the association between cardiac history and post-stroke depression (PSD) in Chinese stroke patients, with the aim of identifying high-risk groups, promoting early intervention strategies, and enhancing patient prognosis. This study was based on data from the 2020 China Health and Retirement Longitudinal Study (CHARLS), which included 933 respondents with a history of stroke. Univariate and multivariate logistic regression analyses were used to assess the effects of cardiac history and other variables on post-stroke depression (PSD). The results indicated a correlation between cardiac history and post-stroke depression (PSD). In addition, the data showed that gender, activities of daily living (ADLs), cognitive functioning, and life satisfaction also had an effect on post-stroke depression (PSD). The findings presented here indicate that patients with a history of cardiac disease are more likely to develop post-stroke depression. This provides valuable insights into the clinical management of stroke patients and the prevention of post-stroke depression. The emotional health assessment of such patients should be emphasized in clinical management, and appropriate psychological support and interventions should be provided to improve their overall prognosis.
format Article
id doaj-art-470a91d8d2d24ee6b14f21e29a6de7d4
institution OA Journals
issn 2045-2322
language English
publishDate 2025-04-01
publisher Nature Portfolio
record_format Article
series Scientific Reports
spelling doaj-art-470a91d8d2d24ee6b14f21e29a6de7d42025-08-20T02:12:01ZengNature PortfolioScientific Reports2045-23222025-04-0115111610.1038/s41598-025-93308-7Cardiac history and post-stroke depression association in Chinese stroke survivors: a cross sectional studyLongxiao Liu0Peng Qin1Jing Bai2Yupei Cheng3Jingjie Huang4Zihe Wang5Yuxing Zhang6Bangqi Wu7Tianjin University of Traditional Chinese MedicineFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine/National Clinical Research Center for Chinese Medicine Acupuncture and MoxibustionTianjin University of Traditional Chinese MedicineTianjin University of Traditional Chinese MedicineTianjin University of Traditional Chinese MedicineTianjin University of Traditional Chinese MedicineTianjin University of Traditional Chinese MedicineFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine/National Clinical Research Center for Chinese Medicine Acupuncture and MoxibustionAbstract A substantial body of evidence indicates that stroke is a primary cause of death and disability on a global scale. The presence of post-stroke depression has been demonstrated to exert a substantial influence on the prognosis of stroke patients, underscoring the imperative for the identification and early prevention of post-stroke depression. The objective of this study was to examine the association between cardiac history and post-stroke depression (PSD) in Chinese stroke patients, with the aim of identifying high-risk groups, promoting early intervention strategies, and enhancing patient prognosis. This study was based on data from the 2020 China Health and Retirement Longitudinal Study (CHARLS), which included 933 respondents with a history of stroke. Univariate and multivariate logistic regression analyses were used to assess the effects of cardiac history and other variables on post-stroke depression (PSD). The results indicated a correlation between cardiac history and post-stroke depression (PSD). In addition, the data showed that gender, activities of daily living (ADLs), cognitive functioning, and life satisfaction also had an effect on post-stroke depression (PSD). The findings presented here indicate that patients with a history of cardiac disease are more likely to develop post-stroke depression. This provides valuable insights into the clinical management of stroke patients and the prevention of post-stroke depression. The emotional health assessment of such patients should be emphasized in clinical management, and appropriate psychological support and interventions should be provided to improve their overall prognosis.https://doi.org/10.1038/s41598-025-93308-7Post-stroke depressionCardiovascular disease historyStrokeCross-sectional studyDepressionCharls
spellingShingle Longxiao Liu
Peng Qin
Jing Bai
Yupei Cheng
Jingjie Huang
Zihe Wang
Yuxing Zhang
Bangqi Wu
Cardiac history and post-stroke depression association in Chinese stroke survivors: a cross sectional study
Scientific Reports
Post-stroke depression
Cardiovascular disease history
Stroke
Cross-sectional study
Depression
Charls
title Cardiac history and post-stroke depression association in Chinese stroke survivors: a cross sectional study
title_full Cardiac history and post-stroke depression association in Chinese stroke survivors: a cross sectional study
title_fullStr Cardiac history and post-stroke depression association in Chinese stroke survivors: a cross sectional study
title_full_unstemmed Cardiac history and post-stroke depression association in Chinese stroke survivors: a cross sectional study
title_short Cardiac history and post-stroke depression association in Chinese stroke survivors: a cross sectional study
title_sort cardiac history and post stroke depression association in chinese stroke survivors a cross sectional study
topic Post-stroke depression
Cardiovascular disease history
Stroke
Cross-sectional study
Depression
Charls
url https://doi.org/10.1038/s41598-025-93308-7
work_keys_str_mv AT longxiaoliu cardiachistoryandpoststrokedepressionassociationinchinesestrokesurvivorsacrosssectionalstudy
AT pengqin cardiachistoryandpoststrokedepressionassociationinchinesestrokesurvivorsacrosssectionalstudy
AT jingbai cardiachistoryandpoststrokedepressionassociationinchinesestrokesurvivorsacrosssectionalstudy
AT yupeicheng cardiachistoryandpoststrokedepressionassociationinchinesestrokesurvivorsacrosssectionalstudy
AT jingjiehuang cardiachistoryandpoststrokedepressionassociationinchinesestrokesurvivorsacrosssectionalstudy
AT zihewang cardiachistoryandpoststrokedepressionassociationinchinesestrokesurvivorsacrosssectionalstudy
AT yuxingzhang cardiachistoryandpoststrokedepressionassociationinchinesestrokesurvivorsacrosssectionalstudy
AT bangqiwu cardiachistoryandpoststrokedepressionassociationinchinesestrokesurvivorsacrosssectionalstudy