Intraocular pressure control after trabeculectomy in the patients with primary open angle glaucoma and pseudoexfoliative glaucoma followed up for 3 to 5 years
Background/Aim. Trabeculectomy is a safe procedure which effectively reduces the intraocular pressure (IOP). IOP is the most frequent indicator of success after glaucoma surgery. The aim of this work was to evaluate the long-term pressure control in primary open-angle glaucoma (POAG) and in pseudoex...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2019-01-01
|
| Series: | Vojnosanitetski Pregled |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2019/0042-84501700178M.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850182357526511616 |
|---|---|
| author | Marić Vesna Marković Vujica Božić Marija Marjanović Ivan Hentova-Senćanić Paraskeva Kontić Đorđe |
| author_facet | Marić Vesna Marković Vujica Božić Marija Marjanović Ivan Hentova-Senćanić Paraskeva Kontić Đorđe |
| author_sort | Marić Vesna |
| collection | DOAJ |
| description | Background/Aim. Trabeculectomy is a safe procedure which effectively reduces the intraocular pressure (IOP). IOP is the most frequent indicator of success after glaucoma surgery. The aim of this work was to evaluate the long-term pressure control in primary open-angle glaucoma (POAG) and in pseudoexfoliative glaucoma (XFG) after primary trabeculectomy without the use of mitomycin-C (MMC), 3 to 5 years after trabeculectomy. Methods. This study involved a retrospective evaluation of 332 consecutive patients (352 eyes), 174 patients (188 eyes) with POAG (mean age of 64.0 ± 8.6 years) and 158 patients (164 eyes) with XFG (mean age of 70.7 ± 8.9 years) who underwent primary trabeculectomy between January 2007 and December 2009 at the Clinic for Eye Diseases, Clinical Center of Serbia in Belgrade. A successful control of IOP was defined as achieving IOP ≤ 21 mmHg without medication (complete success), or with a single topical medication (qualified success). Results. According to the type of glaucoma POAG/XFG preoperative IOP was 28.4 ± 6.3/30.4 ± 8.4 mmHg, respectively (p = 0.311) and last postoperative IOP was 16.9 ± 5.2/18.7 ± 5.9 mmHg, respectively (p = 0.681). According to the Kaplan-Meier survival curve, the complete success in the group with POAG in 1, 3 and 5 years were 85%, 75% and 58% and in the group with XFG were 82%, 70% and 56%, respectively. There was no statistically significant difference in the complete success rates between the patients with POAG and XFG. Conclusion. The primary goal of surgery was to achieve a sufficiently low IOP without additional medication, thus preventing progression of glaucomatous damage. In our study, the complete success in the group with POAG was achieved in 75% and 58% of the patients in the period of 3 and 5 years after surgery, respectively and in the group with XFG complete success was achieved in 70% and 56% of the patients respectively. |
| format | Article |
| id | doaj-art-4700a7c28c564c4897a86d4cfe99bc0f |
| institution | OA Journals |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-4700a7c28c564c4897a86d4cfe99bc0f2025-08-20T02:17:38ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202019-01-0176882282910.2298/VSP161228178M0042-84501700178MIntraocular pressure control after trabeculectomy in the patients with primary open angle glaucoma and pseudoexfoliative glaucoma followed up for 3 to 5 yearsMarić Vesna0Marković Vujica1Božić Marija2Marjanović Ivan3Hentova-Senćanić Paraskeva4Kontić Đorđe5nemanemanemanemanemanemaBackground/Aim. Trabeculectomy is a safe procedure which effectively reduces the intraocular pressure (IOP). IOP is the most frequent indicator of success after glaucoma surgery. The aim of this work was to evaluate the long-term pressure control in primary open-angle glaucoma (POAG) and in pseudoexfoliative glaucoma (XFG) after primary trabeculectomy without the use of mitomycin-C (MMC), 3 to 5 years after trabeculectomy. Methods. This study involved a retrospective evaluation of 332 consecutive patients (352 eyes), 174 patients (188 eyes) with POAG (mean age of 64.0 ± 8.6 years) and 158 patients (164 eyes) with XFG (mean age of 70.7 ± 8.9 years) who underwent primary trabeculectomy between January 2007 and December 2009 at the Clinic for Eye Diseases, Clinical Center of Serbia in Belgrade. A successful control of IOP was defined as achieving IOP ≤ 21 mmHg without medication (complete success), or with a single topical medication (qualified success). Results. According to the type of glaucoma POAG/XFG preoperative IOP was 28.4 ± 6.3/30.4 ± 8.4 mmHg, respectively (p = 0.311) and last postoperative IOP was 16.9 ± 5.2/18.7 ± 5.9 mmHg, respectively (p = 0.681). According to the Kaplan-Meier survival curve, the complete success in the group with POAG in 1, 3 and 5 years were 85%, 75% and 58% and in the group with XFG were 82%, 70% and 56%, respectively. There was no statistically significant difference in the complete success rates between the patients with POAG and XFG. Conclusion. The primary goal of surgery was to achieve a sufficiently low IOP without additional medication, thus preventing progression of glaucomatous damage. In our study, the complete success in the group with POAG was achieved in 75% and 58% of the patients in the period of 3 and 5 years after surgery, respectively and in the group with XFG complete success was achieved in 70% and 56% of the patients respectively.http://www.doiserbia.nb.rs/img/doi/0042-8450/2019/0042-84501700178M.pdfglaucoma open angleexfoliation syndrometrabeculectomyintraocular pressuretreatment outcome |
| spellingShingle | Marić Vesna Marković Vujica Božić Marija Marjanović Ivan Hentova-Senćanić Paraskeva Kontić Đorđe Intraocular pressure control after trabeculectomy in the patients with primary open angle glaucoma and pseudoexfoliative glaucoma followed up for 3 to 5 years Vojnosanitetski Pregled glaucoma open angle exfoliation syndrome trabeculectomy intraocular pressure treatment outcome |
| title | Intraocular pressure control after trabeculectomy in the patients with primary open angle glaucoma and pseudoexfoliative glaucoma followed up for 3 to 5 years |
| title_full | Intraocular pressure control after trabeculectomy in the patients with primary open angle glaucoma and pseudoexfoliative glaucoma followed up for 3 to 5 years |
| title_fullStr | Intraocular pressure control after trabeculectomy in the patients with primary open angle glaucoma and pseudoexfoliative glaucoma followed up for 3 to 5 years |
| title_full_unstemmed | Intraocular pressure control after trabeculectomy in the patients with primary open angle glaucoma and pseudoexfoliative glaucoma followed up for 3 to 5 years |
| title_short | Intraocular pressure control after trabeculectomy in the patients with primary open angle glaucoma and pseudoexfoliative glaucoma followed up for 3 to 5 years |
| title_sort | intraocular pressure control after trabeculectomy in the patients with primary open angle glaucoma and pseudoexfoliative glaucoma followed up for 3 to 5 years |
| topic | glaucoma open angle exfoliation syndrome trabeculectomy intraocular pressure treatment outcome |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2019/0042-84501700178M.pdf |
| work_keys_str_mv | AT maricvesna intraocularpressurecontrolaftertrabeculectomyinthepatientswithprimaryopenangleglaucomaandpseudoexfoliativeglaucomafollowedupfor3to5years AT markovicvujica intraocularpressurecontrolaftertrabeculectomyinthepatientswithprimaryopenangleglaucomaandpseudoexfoliativeglaucomafollowedupfor3to5years AT bozicmarija intraocularpressurecontrolaftertrabeculectomyinthepatientswithprimaryopenangleglaucomaandpseudoexfoliativeglaucomafollowedupfor3to5years AT marjanovicivan intraocularpressurecontrolaftertrabeculectomyinthepatientswithprimaryopenangleglaucomaandpseudoexfoliativeglaucomafollowedupfor3to5years AT hentovasencanicparaskeva intraocularpressurecontrolaftertrabeculectomyinthepatientswithprimaryopenangleglaucomaandpseudoexfoliativeglaucomafollowedupfor3to5years AT konticđorđe intraocularpressurecontrolaftertrabeculectomyinthepatientswithprimaryopenangleglaucomaandpseudoexfoliativeglaucomafollowedupfor3to5years |