Is It Stevens–Johnson Syndrome or MIS-C with Mucocutaneous Involvement?
Background. Severe acute respiratory syndrome coronavirus-2 (SARS-COV-2) can be present in the form of multisystem inflammatory disease in children. Case Presentation. A 25-month-old boy presented with fever, malaise, diffuse maculopapular rashes, and mucosal involvement during the COVID-19 pandemic...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2021/1812545 |
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| author | Abdollah Karimi Elham Pourbakhtiaran Mazdak Fallahi Fereshteh karbasian Shahnaz Armin Delara Babaie |
| author_facet | Abdollah Karimi Elham Pourbakhtiaran Mazdak Fallahi Fereshteh karbasian Shahnaz Armin Delara Babaie |
| author_sort | Abdollah Karimi |
| collection | DOAJ |
| description | Background. Severe acute respiratory syndrome coronavirus-2 (SARS-COV-2) can be present in the form of multisystem inflammatory disease in children. Case Presentation. A 25-month-old boy presented with fever, malaise, diffuse maculopapular rashes, and mucosal involvement during the COVID-19 pandemic. He was first diagnosed with Stevens–Johnson syndrome (SJS). Further evaluation revealed lymphopenia, thrombocytopenia, and elevated levels of C-reactive protein (CRP), ferritin, and fibrinogen. This was followed by a positive polymerase chain reaction (PCR) test for COVID-19. In addition to receiving initial care for SJS, he was treated for MIS-C, which led to his recovery after four days. Conclusion. COVID-19 infection should be considered in children with fever and dermatological features during the pandemic because it may cause different features of the multisystem inflammatory syndrome in children (MIS-C), suggestive of delayed hyperimmune response. |
| format | Article |
| id | doaj-art-46fde3587a2d4c389a8999a4d36f4a8e |
| institution | Kabale University |
| issn | 2090-6811 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-46fde3587a2d4c389a8999a4d36f4a8e2025-02-03T05:47:00ZengWileyCase Reports in Pediatrics2090-68112021-01-01202110.1155/2021/1812545Is It Stevens–Johnson Syndrome or MIS-C with Mucocutaneous Involvement?Abdollah Karimi0Elham Pourbakhtiaran1Mazdak Fallahi2Fereshteh karbasian3Shahnaz Armin4Delara Babaie5Pediatric Infections Research CenterPediatric Infections Research CenterDepartment of Allergy and Clinical ImmunologyDepartment of Pediatric Gastroenterology and HepatologyPediatric Infections Research CenterDepartment of Allergy and Clinical ImmunologyBackground. Severe acute respiratory syndrome coronavirus-2 (SARS-COV-2) can be present in the form of multisystem inflammatory disease in children. Case Presentation. A 25-month-old boy presented with fever, malaise, diffuse maculopapular rashes, and mucosal involvement during the COVID-19 pandemic. He was first diagnosed with Stevens–Johnson syndrome (SJS). Further evaluation revealed lymphopenia, thrombocytopenia, and elevated levels of C-reactive protein (CRP), ferritin, and fibrinogen. This was followed by a positive polymerase chain reaction (PCR) test for COVID-19. In addition to receiving initial care for SJS, he was treated for MIS-C, which led to his recovery after four days. Conclusion. COVID-19 infection should be considered in children with fever and dermatological features during the pandemic because it may cause different features of the multisystem inflammatory syndrome in children (MIS-C), suggestive of delayed hyperimmune response.http://dx.doi.org/10.1155/2021/1812545 |
| spellingShingle | Abdollah Karimi Elham Pourbakhtiaran Mazdak Fallahi Fereshteh karbasian Shahnaz Armin Delara Babaie Is It Stevens–Johnson Syndrome or MIS-C with Mucocutaneous Involvement? Case Reports in Pediatrics |
| title | Is It Stevens–Johnson Syndrome or MIS-C with Mucocutaneous Involvement? |
| title_full | Is It Stevens–Johnson Syndrome or MIS-C with Mucocutaneous Involvement? |
| title_fullStr | Is It Stevens–Johnson Syndrome or MIS-C with Mucocutaneous Involvement? |
| title_full_unstemmed | Is It Stevens–Johnson Syndrome or MIS-C with Mucocutaneous Involvement? |
| title_short | Is It Stevens–Johnson Syndrome or MIS-C with Mucocutaneous Involvement? |
| title_sort | is it stevens johnson syndrome or mis c with mucocutaneous involvement |
| url | http://dx.doi.org/10.1155/2021/1812545 |
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