Therapeutic Application of rTMS in Atypical Parkinsonian Disorders
The terms atypical parkinsonian disorders (APDs) and Parkinson plus syndromes are mainly used to describe the four major entities of sporadic neuronal multisystem degeneration: progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), multiple system atrophy (MSA), and dementia with Lew...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Behavioural Neurology |
| Online Access: | http://dx.doi.org/10.1155/2021/3419907 |
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| author | Chrysi Petsani Athina-Maria Aloizou Vasileios Siokas Lambros Messinis Eleni Peristeri Christos Bakirtzis Grigorios Nasios Efthimios Dardiotis |
| author_facet | Chrysi Petsani Athina-Maria Aloizou Vasileios Siokas Lambros Messinis Eleni Peristeri Christos Bakirtzis Grigorios Nasios Efthimios Dardiotis |
| author_sort | Chrysi Petsani |
| collection | DOAJ |
| description | The terms atypical parkinsonian disorders (APDs) and Parkinson plus syndromes are mainly used to describe the four major entities of sporadic neuronal multisystem degeneration: progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), multiple system atrophy (MSA), and dementia with Lewy bodies (LBD). APDs are characterized by a variety of symptoms and a lack of disease modifying therapies; their treatment thus remains mainly symptomatic. Brain stimulation via repetitive transcranial magnetic stimulation (rTMS) is a safe and noninvasive intervention using a magnetic coil, and it is considered an alternative therapy in various neuropsychiatric pathologies. In this paper, we review the available studies that investigate the efficacy of rTMS in the treatment of these APDs and Parkinson plus syndromes. Τhe majority of the studies have shown beneficial effects on motor and nonmotor symptoms, but research is still at a preliminary phase, with large, double-blind studies lacking in the literature. |
| format | Article |
| id | doaj-art-46d4560eb59646b0871257fe495762a8 |
| institution | Kabale University |
| issn | 1875-8584 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Behavioural Neurology |
| spelling | doaj-art-46d4560eb59646b0871257fe495762a82025-02-03T05:59:59ZengWileyBehavioural Neurology1875-85842021-01-01202110.1155/2021/3419907Therapeutic Application of rTMS in Atypical Parkinsonian DisordersChrysi Petsani0Athina-Maria Aloizou1Vasileios Siokas2Lambros Messinis3Eleni Peristeri4Christos Bakirtzis5Grigorios Nasios6Efthimios Dardiotis7Department of NeurologyDepartment of NeurologyDepartment of NeurologySchool of PsychologyDepartment of English StudiesMultiple Sclerosis CenterDepartment of Speech and Language TherapyDepartment of NeurologyThe terms atypical parkinsonian disorders (APDs) and Parkinson plus syndromes are mainly used to describe the four major entities of sporadic neuronal multisystem degeneration: progressive supranuclear palsy (PSP), corticobasal degeneration (CBD), multiple system atrophy (MSA), and dementia with Lewy bodies (LBD). APDs are characterized by a variety of symptoms and a lack of disease modifying therapies; their treatment thus remains mainly symptomatic. Brain stimulation via repetitive transcranial magnetic stimulation (rTMS) is a safe and noninvasive intervention using a magnetic coil, and it is considered an alternative therapy in various neuropsychiatric pathologies. In this paper, we review the available studies that investigate the efficacy of rTMS in the treatment of these APDs and Parkinson plus syndromes. Τhe majority of the studies have shown beneficial effects on motor and nonmotor symptoms, but research is still at a preliminary phase, with large, double-blind studies lacking in the literature.http://dx.doi.org/10.1155/2021/3419907 |
| spellingShingle | Chrysi Petsani Athina-Maria Aloizou Vasileios Siokas Lambros Messinis Eleni Peristeri Christos Bakirtzis Grigorios Nasios Efthimios Dardiotis Therapeutic Application of rTMS in Atypical Parkinsonian Disorders Behavioural Neurology |
| title | Therapeutic Application of rTMS in Atypical Parkinsonian Disorders |
| title_full | Therapeutic Application of rTMS in Atypical Parkinsonian Disorders |
| title_fullStr | Therapeutic Application of rTMS in Atypical Parkinsonian Disorders |
| title_full_unstemmed | Therapeutic Application of rTMS in Atypical Parkinsonian Disorders |
| title_short | Therapeutic Application of rTMS in Atypical Parkinsonian Disorders |
| title_sort | therapeutic application of rtms in atypical parkinsonian disorders |
| url | http://dx.doi.org/10.1155/2021/3419907 |
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