Acemannan Induced Bone Regeneration in Lateral Sinus Augmentation Based on Cone Beam Computed Tomographic and Histopathological Evaluation
Acemannan, the major polysaccharide extracted from Aloe vera, is biomaterial that has demonstrated osteoinductive effects in vitro and in vivo. However, the effect of acemannan sponges on bone formation in open-type sinus augmentation has not evaluated. Here, we report a case study using radiographi...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2020/1675653 |
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| author | Hai Anh Trinh Van Viet Dam Wijit Banlunara Polkit Sangvanich Pasutha Thunyakitpisal |
| author_facet | Hai Anh Trinh Van Viet Dam Wijit Banlunara Polkit Sangvanich Pasutha Thunyakitpisal |
| author_sort | Hai Anh Trinh |
| collection | DOAJ |
| description | Acemannan, the major polysaccharide extracted from Aloe vera, is biomaterial that has demonstrated osteoinductive effects in vitro and in vivo. However, the effect of acemannan sponges on bone formation in open-type sinus augmentation has not evaluated. Here, we report a case study using radiographic and histological analyses to investigate the effect of acemannan on bone formation after lateral sinus lift surgery. The case was a 57-year-old female patient with an atrophic left posterior maxilla who underwent lateral sinus lift using an acemannan sponge using the two-stage procedure. In the first stage, an acemannan sponge was inserted through the bony window and placed between the antral floor and the elevated sinus membrane. Cone beam computed tomography (CBCT) images were taken immediately as baseline and 6-month postoperation for evaluation. A bone core specimen was also obtained for histological examination at the time of implant placement. The histological results revealed new bone formation, and the CBCT images demonstrated increased alveolar bone height at 6-month postoperation. Our findings suggest that an acemannan sponge could be a biomaterial for inducing bone formation in sinus lift surgery. |
| format | Article |
| id | doaj-art-46d2236bbe7f4f49a84d869341893629 |
| institution | Kabale University |
| issn | 2090-6447 2090-6455 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dentistry |
| spelling | doaj-art-46d2236bbe7f4f49a84d8693418936292025-02-03T05:49:55ZengWileyCase Reports in Dentistry2090-64472090-64552020-01-01202010.1155/2020/16756531675653Acemannan Induced Bone Regeneration in Lateral Sinus Augmentation Based on Cone Beam Computed Tomographic and Histopathological EvaluationHai Anh Trinh0Van Viet Dam1Wijit Banlunara2Polkit Sangvanich3Pasutha Thunyakitpisal4Multidisciplinary Dental Biomaterials Science Program, Graduate School, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Implantology, Hanoi National Hospital of Odonto-Stomatology, Hanoi 100000, VietnamDepartment of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, ThailandDepartment of Anatomy, Multidisciplinary Dental Biomaterials Science Program, Research Unit of Herbal Medicine, Biomaterial and Material for Dental Treatment, Faculty of Dentistry, Chulalongkorn University, Bangkok 10330, ThailandAcemannan, the major polysaccharide extracted from Aloe vera, is biomaterial that has demonstrated osteoinductive effects in vitro and in vivo. However, the effect of acemannan sponges on bone formation in open-type sinus augmentation has not evaluated. Here, we report a case study using radiographic and histological analyses to investigate the effect of acemannan on bone formation after lateral sinus lift surgery. The case was a 57-year-old female patient with an atrophic left posterior maxilla who underwent lateral sinus lift using an acemannan sponge using the two-stage procedure. In the first stage, an acemannan sponge was inserted through the bony window and placed between the antral floor and the elevated sinus membrane. Cone beam computed tomography (CBCT) images were taken immediately as baseline and 6-month postoperation for evaluation. A bone core specimen was also obtained for histological examination at the time of implant placement. The histological results revealed new bone formation, and the CBCT images demonstrated increased alveolar bone height at 6-month postoperation. Our findings suggest that an acemannan sponge could be a biomaterial for inducing bone formation in sinus lift surgery.http://dx.doi.org/10.1155/2020/1675653 |
| spellingShingle | Hai Anh Trinh Van Viet Dam Wijit Banlunara Polkit Sangvanich Pasutha Thunyakitpisal Acemannan Induced Bone Regeneration in Lateral Sinus Augmentation Based on Cone Beam Computed Tomographic and Histopathological Evaluation Case Reports in Dentistry |
| title | Acemannan Induced Bone Regeneration in Lateral Sinus Augmentation Based on Cone Beam Computed Tomographic and Histopathological Evaluation |
| title_full | Acemannan Induced Bone Regeneration in Lateral Sinus Augmentation Based on Cone Beam Computed Tomographic and Histopathological Evaluation |
| title_fullStr | Acemannan Induced Bone Regeneration in Lateral Sinus Augmentation Based on Cone Beam Computed Tomographic and Histopathological Evaluation |
| title_full_unstemmed | Acemannan Induced Bone Regeneration in Lateral Sinus Augmentation Based on Cone Beam Computed Tomographic and Histopathological Evaluation |
| title_short | Acemannan Induced Bone Regeneration in Lateral Sinus Augmentation Based on Cone Beam Computed Tomographic and Histopathological Evaluation |
| title_sort | acemannan induced bone regeneration in lateral sinus augmentation based on cone beam computed tomographic and histopathological evaluation |
| url | http://dx.doi.org/10.1155/2020/1675653 |
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