A Multivent System for Non-Invasive Ventilation: Solving the Problem of Ventilator Shortage During the COVID-19 Pandemic

The COVID-19 pandemic has caused a severe global problem of ventilator shortage. Placing multiple patients on a single ventilator (ventilator sharing) or dual patient ventilation has been proposed and conducted to increase the cure efficiency for ventilated patients. However, the ventilator-sharing...

Full description

Saved in:
Bibliographic Details
Main Authors: Shuai Ren, Xiaohan Wang, Liming Hao, Tao Wang, Zujin Luo
Format: Article
Language:English
Published: IEEE 2023-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/10129919/
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832540524036227072
author Shuai Ren
Xiaohan Wang
Liming Hao
Tao Wang
Zujin Luo
author_facet Shuai Ren
Xiaohan Wang
Liming Hao
Tao Wang
Zujin Luo
author_sort Shuai Ren
collection DOAJ
description The COVID-19 pandemic has caused a severe global problem of ventilator shortage. Placing multiple patients on a single ventilator (ventilator sharing) or dual patient ventilation has been proposed and conducted to increase the cure efficiency for ventilated patients. However, the ventilator-sharing method needs to use the same ventilator settings for all the patients, which cannot meet the ventilation needs of different patients. Therefore, a novel multivent system for non-invasive ventilation has been proposed in this study. The close loop system consists of the proportional valve and the flow-pressure sensor can regulate the airway pressure and flow for each patient. Multiple ventilation circuits can be combined in parallel to simultaneously meet patients’ ventilation demands. Meanwhile, the mathematical model of the multivent system is established and validated through experiments. The experiments for different inspired positive airway pressure (IPAP), expired positive airway pressure (EPAP), inspiratory expiratory ratio (I:E), and breath per minute (BPM) have been conducted and analyzed to test the performance of the multivent system. The results show that the multivent system can realize the biphasic positive airway pressure (BIPAP) ventilation mode in non-invasive ventilation without interfering among the three ventilation circuits, no matter the change of IPAP, EPAP, I:E, and BPM. However, pressure fluctuation exists during the ventilation process because of the exhaust valve effect, especially in EPAP control. The control accuracy and stability need to be improved. Nevertheless, the novel designed multivent system can bring innovation to the current mechanical ventilation system and solve the problem of ventilator shortage for major, new, and emerging respiratory infectious diseases in the future.
format Article
id doaj-art-46d013ebac6e4f3fb7c9fd8d43f7ba9d
institution Kabale University
issn 2169-3536
language English
publishDate 2023-01-01
publisher IEEE
record_format Article
series IEEE Access
spelling doaj-art-46d013ebac6e4f3fb7c9fd8d43f7ba9d2025-02-05T00:00:36ZengIEEEIEEE Access2169-35362023-01-0111498744988110.1109/ACCESS.2023.327810310129919A Multivent System for Non-Invasive Ventilation: Solving the Problem of Ventilator Shortage During the COVID-19 PandemicShuai Ren0https://orcid.org/0000-0003-4407-0265Xiaohan Wang1Liming Hao2https://orcid.org/0000-0002-9478-8171Tao Wang3https://orcid.org/0000-0002-4746-8159Zujin Luo4School of Automation, Beijing Institute of Technology, Beijing, ChinaSchool of Automation, Beijing Institute of Technology, Beijing, ChinaSchool of Automation Science and Electrical Engineering, Beihang University, Beijing, ChinaSchool of Automation, Beijing Institute of Technology, Beijing, ChinaDepartment of Respiratory and Critical Care Medicine, Beijing Engineering Research Center of Respiratory and Critical Care Medicine, Beijing Institute of Respiratory Medicine, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, ChinaThe COVID-19 pandemic has caused a severe global problem of ventilator shortage. Placing multiple patients on a single ventilator (ventilator sharing) or dual patient ventilation has been proposed and conducted to increase the cure efficiency for ventilated patients. However, the ventilator-sharing method needs to use the same ventilator settings for all the patients, which cannot meet the ventilation needs of different patients. Therefore, a novel multivent system for non-invasive ventilation has been proposed in this study. The close loop system consists of the proportional valve and the flow-pressure sensor can regulate the airway pressure and flow for each patient. Multiple ventilation circuits can be combined in parallel to simultaneously meet patients’ ventilation demands. Meanwhile, the mathematical model of the multivent system is established and validated through experiments. The experiments for different inspired positive airway pressure (IPAP), expired positive airway pressure (EPAP), inspiratory expiratory ratio (I:E), and breath per minute (BPM) have been conducted and analyzed to test the performance of the multivent system. The results show that the multivent system can realize the biphasic positive airway pressure (BIPAP) ventilation mode in non-invasive ventilation without interfering among the three ventilation circuits, no matter the change of IPAP, EPAP, I:E, and BPM. However, pressure fluctuation exists during the ventilation process because of the exhaust valve effect, especially in EPAP control. The control accuracy and stability need to be improved. Nevertheless, the novel designed multivent system can bring innovation to the current mechanical ventilation system and solve the problem of ventilator shortage for major, new, and emerging respiratory infectious diseases in the future.https://ieeexplore.ieee.org/document/10129919/Mechanical ventilationmultivent systempneumatic systemproportional control
spellingShingle Shuai Ren
Xiaohan Wang
Liming Hao
Tao Wang
Zujin Luo
A Multivent System for Non-Invasive Ventilation: Solving the Problem of Ventilator Shortage During the COVID-19 Pandemic
IEEE Access
Mechanical ventilation
multivent system
pneumatic system
proportional control
title A Multivent System for Non-Invasive Ventilation: Solving the Problem of Ventilator Shortage During the COVID-19 Pandemic
title_full A Multivent System for Non-Invasive Ventilation: Solving the Problem of Ventilator Shortage During the COVID-19 Pandemic
title_fullStr A Multivent System for Non-Invasive Ventilation: Solving the Problem of Ventilator Shortage During the COVID-19 Pandemic
title_full_unstemmed A Multivent System for Non-Invasive Ventilation: Solving the Problem of Ventilator Shortage During the COVID-19 Pandemic
title_short A Multivent System for Non-Invasive Ventilation: Solving the Problem of Ventilator Shortage During the COVID-19 Pandemic
title_sort multivent system for non invasive ventilation solving the problem of ventilator shortage during the covid 19 pandemic
topic Mechanical ventilation
multivent system
pneumatic system
proportional control
url https://ieeexplore.ieee.org/document/10129919/
work_keys_str_mv AT shuairen amultiventsystemfornoninvasiveventilationsolvingtheproblemofventilatorshortageduringthecovid19pandemic
AT xiaohanwang amultiventsystemfornoninvasiveventilationsolvingtheproblemofventilatorshortageduringthecovid19pandemic
AT liminghao amultiventsystemfornoninvasiveventilationsolvingtheproblemofventilatorshortageduringthecovid19pandemic
AT taowang amultiventsystemfornoninvasiveventilationsolvingtheproblemofventilatorshortageduringthecovid19pandemic
AT zujinluo amultiventsystemfornoninvasiveventilationsolvingtheproblemofventilatorshortageduringthecovid19pandemic
AT shuairen multiventsystemfornoninvasiveventilationsolvingtheproblemofventilatorshortageduringthecovid19pandemic
AT xiaohanwang multiventsystemfornoninvasiveventilationsolvingtheproblemofventilatorshortageduringthecovid19pandemic
AT liminghao multiventsystemfornoninvasiveventilationsolvingtheproblemofventilatorshortageduringthecovid19pandemic
AT taowang multiventsystemfornoninvasiveventilationsolvingtheproblemofventilatorshortageduringthecovid19pandemic
AT zujinluo multiventsystemfornoninvasiveventilationsolvingtheproblemofventilatorshortageduringthecovid19pandemic