Refractory Immunological Thrombocytopenia Purpura and Splenectomy in Pregnancy
Thrombocytopenia is defined as a platelet count of less than 100,000 platelets per microlitre (mcL). Thrombocytopenia develops in approximately 6-7% of women during pregnancy and at least 3% of these cases are caused by immunological platelet destruction. Herein, we present a pregnant woman who deve...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Immunology |
| Online Access: | http://dx.doi.org/10.1155/2015/216362 |
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| author | Santiago Bernal-Macías Laura-Marcela Fino-Velásquez Felipe E. Vargas-Barato Lucio Guerra-Galue Benjamín Reyes-Beltrán Adriana Rojas-Villarraga |
| author_facet | Santiago Bernal-Macías Laura-Marcela Fino-Velásquez Felipe E. Vargas-Barato Lucio Guerra-Galue Benjamín Reyes-Beltrán Adriana Rojas-Villarraga |
| author_sort | Santiago Bernal-Macías |
| collection | DOAJ |
| description | Thrombocytopenia is defined as a platelet count of less than 100,000 platelets per microlitre (mcL). Thrombocytopenia develops in approximately 6-7% of women during pregnancy and at least 3% of these cases are caused by immunological platelet destruction. Herein, we present a pregnant woman who develops at the first trimester autoimmune thrombocytopenia purpura associated with positive antiphospholipid antibodies. The disease was refractory to pharmacological treatments but had a favourable response to splenectomy. The patient carried the pregnancy to term without complication and gave birth to a healthy baby girl. |
| format | Article |
| id | doaj-art-468a8ea25fca47faafd5da719affc3e8 |
| institution | Kabale University |
| issn | 2090-6609 2090-6617 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Immunology |
| spelling | doaj-art-468a8ea25fca47faafd5da719affc3e82025-02-03T07:25:39ZengWileyCase Reports in Immunology2090-66092090-66172015-01-01201510.1155/2015/216362216362Refractory Immunological Thrombocytopenia Purpura and Splenectomy in PregnancySantiago Bernal-Macías0Laura-Marcela Fino-Velásquez1Felipe E. Vargas-Barato2Lucio Guerra-Galue3Benjamín Reyes-Beltrán4Adriana Rojas-Villarraga5Center for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Bogotá, ColombiaCenter for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Bogotá, ColombiaSurgery Department, School of Medicine and Health Sciences, Universidad del Rosario, Bogotá, ColombiaGynaecology Department, Hospital Universitario Mayor-Mederi (HUM), Bogotá, ColombiaCenter for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Bogotá, ColombiaCenter for Autoimmune Diseases Research (CREA), School of Medicine and Health Sciences, Universidad del Rosario, Bogotá, ColombiaThrombocytopenia is defined as a platelet count of less than 100,000 platelets per microlitre (mcL). Thrombocytopenia develops in approximately 6-7% of women during pregnancy and at least 3% of these cases are caused by immunological platelet destruction. Herein, we present a pregnant woman who develops at the first trimester autoimmune thrombocytopenia purpura associated with positive antiphospholipid antibodies. The disease was refractory to pharmacological treatments but had a favourable response to splenectomy. The patient carried the pregnancy to term without complication and gave birth to a healthy baby girl.http://dx.doi.org/10.1155/2015/216362 |
| spellingShingle | Santiago Bernal-Macías Laura-Marcela Fino-Velásquez Felipe E. Vargas-Barato Lucio Guerra-Galue Benjamín Reyes-Beltrán Adriana Rojas-Villarraga Refractory Immunological Thrombocytopenia Purpura and Splenectomy in Pregnancy Case Reports in Immunology |
| title | Refractory Immunological Thrombocytopenia Purpura and Splenectomy in Pregnancy |
| title_full | Refractory Immunological Thrombocytopenia Purpura and Splenectomy in Pregnancy |
| title_fullStr | Refractory Immunological Thrombocytopenia Purpura and Splenectomy in Pregnancy |
| title_full_unstemmed | Refractory Immunological Thrombocytopenia Purpura and Splenectomy in Pregnancy |
| title_short | Refractory Immunological Thrombocytopenia Purpura and Splenectomy in Pregnancy |
| title_sort | refractory immunological thrombocytopenia purpura and splenectomy in pregnancy |
| url | http://dx.doi.org/10.1155/2015/216362 |
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