Micro-RNA Expression and Function in Lymphomas

The recent discovery of microRNAs (miRNAs) has introduced a new layer of complexity to the process of gene regulation. MiRNAs are essential for cellular function, and their dysregulation often results in disease. Study of miRNA expression and function in animal models and human lymphomas has improve...

Full description

Saved in:
Bibliographic Details
Main Authors: Sukhinder K. Sandhu, Carlo M. Croce, Ramiro Garzon
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2011/347137
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The recent discovery of microRNAs (miRNAs) has introduced a new layer of complexity to the process of gene regulation. MiRNAs are essential for cellular function, and their dysregulation often results in disease. Study of miRNA expression and function in animal models and human lymphomas has improved our knowledge of the pathogenesis of this heterogeneous disease. In this paper, we attempt to describe the expression of miRNAs and their function in lymphomas and discuss potential miRNA-based therapies in the diagnosis and treatment of lymphomas.
ISSN:1687-9104
1687-9112